Results 141 to 150 of about 31,458 (257)

Comparative analysis of microRNAs in bovine colostrum and neonatal calf blood

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND MicroRNAs (miRNAs) are short non‐coding RNAs that participate in a wide range of biological processes. MiRNAs are present in high concentrations in colostrum, and these may be potentially transferred to newborn calves being fed colostrum.
Do T Hue, Kiro Petrovski, Yan Ren, John L Williams, Tong Chen, Wai Y Low, Thien D Van, Cynthia D K Bottema   +7 more
wiley   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

Interaction of High-Fat Diet and Brain Trauma Alters Adipose Tissue Macrophages and Brain Microglia Associated With Exacerbated Cognitive Dysfunction [PDF]

Obesity increases the morbidity and mortality of traumatic brain injury (TBI). Detailed analyses of transcriptomic changes in the brain and adipose tissue were performed to elucidate the interactive effects between high-fat diet-induced obesity (DIO) and
Barrett, James P, Faden, Alan I, Henry, Rebecca J, Khan, Niaz Z, Makarevich, Oleg, Ritzel, Rodney M, Stoica, Bogdan A, Vaida, Maria   +7 more
core   +2 more sources

Glycolysis-Related LINC02432/Hsa-miR-98-5p/HK2 Axis Inhibits Ferroptosis and Predicts Immune Infiltration, Tumor Mutation Burden, and Drug Sensitivity in Pancreatic Adenocarcinoma. [PDF]

Front Pharmacol, 2022
Tan P, Li M, Liu Z, Li T, Zhao L, Fu W.
europepmc   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Identification and Validation of the miR/RAS/RUNX2 Autophagy Regulatory Network in AngII-Induced Hypertensive Nephropathy in MPC5 Cells Treated with Hydrogen Sulfide Donors

Antioxidants
The balanced crosstalk between miRNAs and autophagy is essential in hypertensive nephropathy. Hydrogen sulfide donors have been reported to attenuate renal injury, but the mechanism is unclear.
Qing Ye, Mi Ren, Di Fan, Yicheng Mao, Yi-Zhun Zhu   +4 more
doaj   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Wall‐to‐wall Amazon forest height mapping with Planet NICFI, Aerial LiDAR, and a U‐Net regression model

Remote Sensing in Ecology and Conservation, EarlyView.
Tree canopy height is a key indicator of forest biomass and structure, yet accurate mapping across the Amazon remains challenging. Here, we generated a canopy height map of the Amazon forest at ~4.8 m resolution using Planet NICFI imagery and a deep learning U‐Net model trained with airborne LiDAR data.
Fabien H. Wagner, Ricardo Dalagnol, Griffin Carter, Mayumi C. M. Hirye, Shivraj Gill, Le Bienfaiteur Sagang Takougoum, Samuel Favrichon, Michael Keller, Jean P. H. B. Ometto, Lorena Alves, Cynthia Creze, Stephanie P. George‐Chacon, Shuang Li, Zhihua Liu, Adugna Mullissa, Yan Yang, Erone G. Santos, Sarah R. Worden, Martin Brandt, Philippe Ciais, Stephen C. Hagen, Sassan Saatchi   +21 more
wiley   +1 more source

Circular RNA hsa_circ_0005519 contributes to acute kidney injury via sponging microRNA-98-5p

BMC Nephrology
Background This study intends to explore the role and molecular mechanism of hsa_circ_0005519 in acute kidney injury (AKI). Methods We conducted reverse transcription-qPCR for human serum to determine levels of hsa_circ_0005519 in AKI patients and ...
Linsen Jiang, Manxin Huang, Jun Ge, Xuefeng Zhang, Ye Liu, Hang Liu, Xiaoming Liu, Lili Jiang   +7 more
doaj   +1 more source

Small RNA sequencing in individually selected sperm: Biomarkers for male subfertility and predictors of pregnancy success

Non-coding RNA Research
Background: Sperm quality defined by motility and morphology has critical implications for fertility and pregnancy outcomes. Small RNAs, including microRNAs (miRNAs) and Piwi-interacting RNAs (piRNAs), play regulatory roles and may reflect underlying ...
Mohammad A. Al Smadi, Haidar Haidar, Albert Salas-Huetos, Ulrike Fischer, Hashim Abdul-Khaliq, Eckart Meese, Masood Abu-Halima   +6 more
doaj   +1 more source