Results 161 to 170 of about 31,458 (257)

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

Cell Proliferation, EarlyView.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang, Jinrui Li, Xingjia Mao, Wanyu Wang, Yansong Li, Xuefei Hu, Jinjie Zhong, Fengdong Zhao, Linlin Wang   +8 more
wiley   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Submicron silica particles have cytotoxicities on hepatocellular carcinoma, non-small cell lung cancer and breast cancer by unified regulating the XLOC_001659/miR-98-5p/MAP3K2-mediated pathway. [PDF]

Toxicol Res (Camb), 2021
Shi J, Ci Y, Zheng Y, Chen W, Chen X.
europepmc   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

The FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia, Jiwang Tang, José C. Casas‐Martinez, Penglin Li, Maria Borja‐Gonzalez, Leo R Quinlan, Katarzyna Goljanek‐Whysall, Brian McDonagh   +7 more
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Microanatomical features of bovids long bones: What are the effects of mass and habitat?

Journal of Anatomy, EarlyView.
This study provides the first qualitative and quantitative exploration of inter‐bones and interspecific variations in the microanatomy of long bones in bovids in response to significant changes in body mass and habitat. Abstract Bovids are a valuable group for studying limb long bone adaptations due to differences in size and the environment that the ...
Morgan Proust, Cyril Etienne, Alexandra Houssaye   +2 more
wiley   +1 more source

Unveiling coralline diversity of mesophotic rhodoliths in subtropical Japan, including new species of Sporolithon, emended genera Orientalilithon and Roseolithon (Corallinophycidae, Rhodophyta)

Journal of Phycology, EarlyView.
Abstract The mesophotic zone off Tanegashima Island (approximately 30–40 m deep) is a marine macroalgal hotspot in subtropical Japan; however, the taxonomic diversity of calcifying red algal community remains poorly understood. Our phylogenetic analyses based on psbA, rbcL, and COI‐5P gene markers disclosed the presence of at least 12 rhodolith‐forming
Min‐Khant‐Kyaw, Masasuke Baba, Ryuta Terada, Aki Kato   +3 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Gallic Acid‐Responsive microRNAs Reprogram Lignification During Drought Acclimation Process in Spearmint

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mentha spicata L. (spearmint) is a high‐value aromatic and medicinal species, whose productivity is strongly affected by water deficit. Nevertheless, the molecular mechanisms underlying drought acclimation in this mint remain largely unexplored. Thus, here, we investigated the microRNA‐mediated regulatory processes triggered in M.
Alessia D'Agostino, Gabriele Di Marco, Gerardo Pepe, Adelaide Teofani, Chiara Pontecorvi, Manuela Helmer‐Citterich, Antonella Canini, Angelo Gismondi   +7 more
wiley   +1 more source

Bone biology in aging periodontal and peri‐implant tissues

Periodontology 2000, EarlyView.
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa, Giuseppe Intini, Daniel Clark   +2 more
wiley   +1 more source