Results 191 to 200 of about 480,809 (228)

Differentially expressed miR-20, miR-21, miR-100, miR-125a and miR-146a as a potential biomarker for prostate cancer

Molecular Biology Reports, 2021
Prostate cancer is the leading cause of death among men worldwide. Deregulation of microRNAs has been reported in many cancers. Expression of microRNAs miR-20a-5p, miR-21-5p, miR-100-5p, miR-125a-5p and miR-146a-5p in tissue blocks of histologically confirmed prostate cancer patients compared with BPH patients, to identify potential microRNA biomarker ...
Mohan Damodaran, Mohanapriya Chinambedu Dandapani, null SimonDuraiRaj, null SandhyaSundaram, S. VenkatRamanan, Ilangovan Ramachandran, Vettriselvi Venkatesan   +6 more
openaire   +2 more sources

MicroRNAs miR-1, miR-133a, miR-133b, miR-208a and miR-208b are dysregulated in Chronic Chagas disease Cardiomyopathy

International Journal of Cardiology, 2014
Chagas disease is caused by an intracellular parasite, Trypanosoma cruzi, and it is a leading cause of heart failure in Latin America. The main clinical consequence of the infection is the development of a Chronic Chagas disease Cardiomyopathy (CCC), which is characterized by myocarditis, hypertrophy and fibrosis and affects about 30% of infected ...
Pinto Ferreira, Ludmila Rodrigues, Frade, Amanda Farage, Barros Santos, Ronaldo Honorato, Teixeira, Priscila Camillo, Baron, Monique Andrade, Navarro, Isabela Cunha, Benvenuti, Luiz Alberto, Fiorelli, Alfredo Inacio, Bocchi, Edimar Alcides, Stolf, Noedir Antonio, Chevillard, Christophe, Kalil, Jorge, Cunha-Neto, Edecio   +12 more
openaire   +2 more sources

Clinicopathological significance of miR‐26, miR‐107, miR‐125b, and miR‐203 in head and neck carcinomas

Oral Diseases, 2018
ObjectivesMicroRNAs play a role in the development and progression of head and neck squamous cell carcinomas (HNSCC). Our aim was to study the expression of miR‐26, miR‐107, miR‐125b, and miR‐203 in primary HNSCC with and without lymph node metastasis and their clinicopathological significance.Materials and MethodsThe expression of microRNAs in primary
WA González‐Arriagada, P Olivero, B Rodríguez, C Lozano‐Burgos, CE de Oliveira, RD Coletta   +5 more
openaire   +2 more sources

Silencing of TERT decreases levels of miR‐1, miR‐21, miR‐29a and miR‐208a in cardiomyocytes

Cell Biochemistry and Function, 2014
To test the hypothesis that telomerase reverse transcriptase (TERT) as an RNA‐dependent RNA polymerase could be involved in the amplification of microRNA (miRNA), we have determined the levels of immature and mature miRNA in cultured neonatal rat cardiomyocytes, during the silencing of TERT by siRNA.
T I, Drevytska, V S, Nagibin, V L, Gurianova, V R, Kedlyan, A A, Moibenko, V E, Dosenko   +5 more
openaire   +2 more sources

MIR-23a, MIR-494, MIR-19b, MIR-96 Expression in Parkinson‘s Disease

2023
Parkinson’s disease is the second leading neurodegenerative disorder in the world that results in bradykinesia and tremor due to the death of dopaminergic neurons. Yet, it is still a challenge to select the best individual treatment and to predict the progression of the disease.
Belickienė, Violeta, Pranckevičienė, Aistė, Radžiūnas, Andrius, Miniotaitė, Giedrė, Vaitkienė, Paulina   +4 more
openaire   +1 more source

The clinical significance of miR-335, miR-124, miR-218 and miR-484 downregulation in gastric cancer

Molecular Biology Reports, 2018
Gastric cancer (GC) is one of the leading types of malignancy worldwide, particularly in Asian populations. Although the exact molecular mechanism of GC development remains unknown, microRNA (miRNA) has recently been shown to be involved. The current study aims to investigate the expression levels of bioinformatically ranked miRNAs in gastric tissues ...
Ali Zare, Alireza Ahadi, Pegah Larki, Mir Davood Omrani, Mohammad Reza Zali, Nasser Malekpour Alamdari, Hamid Ghaedi   +6 more
openaire   +2 more sources

MiR-21, miR-126 and miR-181b expression in Thromboangiitis obliterans

Vasa
Summary: Background: Several studies have demonstrated the participation of by-products of the NF-kB pathway in thromboangiitis obliterans, however, the involvement of microRNAs 21, 126 and 181b that are related to this pathway in TAO activation is unknown.
Breno Pinheiro Rossoni, Juliana Lima Toledo Rossoni, Carlos Augusto Schreiner, Elisa Helena Subtil Zampieri, Daniela Pretti da Cunha Tirapelli, Edwaldo Edner Joviliano   +5 more
openaire   +2 more sources