Results 101 to 110 of about 461,417 (302)

LncRNA A1BG-AS1 regulates the progress of diabetic foot ulcers via sponging miR-214-3p

open access: yesEndocrine Journal
Nerve aberrations and vascular lesions in the distal lower limbs are the etiological factors for diabetic foot ulcers (DFUs). This study aimed to understand the regulatory mechanism of angiogenesis in patients with DFU by examining lncRNA, as well as to ...
Fangfang Wu   +3 more
doaj   +1 more source

Investigating the association of rs1951032 Polymorphism in the pre-miR-487a flanking region with incidence of breast cancer in Iranian women [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2017
Background & Objective: MiRNAs are among non-coding RNAs involved in regulation of the target genes through a direct interaction with the mRNA. Therefore, any variation in the miRNA genes could be effective in modification of the functionality of miRNA ...
Reza Hashemi, Maryam Peymani
doaj  

Optimization of miRNA-seq data preprocessing. [PDF]

open access: yes, 2015
The past two decades of microRNA (miRNA) research has solidified the role of these small non-coding RNAs as key regulators of many biological processes and promising biomarkers for disease.
McPherson, John D   +2 more
core   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello   +2 more
wiley   +1 more source

The role of miRNAs as biomarkers in heterotopic ossification

open access: yesEFORT Open Reviews
Fibrodysplasia ossificans progressiva and progressive osseous heteroplasia are genetic forms of heterotopic ossification (HO). Fibrodysplasia ossificans progressiva is caused by ACVR1 gene mutations, while progressive osseous heteroplasia is caused by ...
Chen Xie   +5 more
doaj   +1 more source

The Network of miRNA–mRNA Interactions in Circulating T Cells of Patients Following Major Trauma – A Pilot Study

open access: yesJournal of Inflammation Research, 2022
Cheng-Shyuan Rau1 *, Pao-Jen Kuo2 *, Hui-Ping Lin,2 Chia-Jung Wu,2 Yi-Chan Wu,2 Peng-Chen Chien,2 Ting-Min Hsieh,3 Hang-Tsung Liu,3 Chun-Ying Huang,3 Ching-Hua Hsieh2 1Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang ...
Rau CS   +9 more
doaj  

Functional Genomics Profiling of Bladder Urothelial Carcinoma MicroRNAome as a Potential Biomarker. [PDF]

open access: yes, 2018
Though bladder urothelial carcinoma is the most common form of bladder cancer, advances in its diagnosis and treatment have been modest in the past few decades.
Li, Wei Tse   +4 more
core   +2 more sources

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

open access: yesAdvanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang   +12 more
wiley   +1 more source

The Relationship Between Larynx Cancer and MicroRNAs

open access: yesVan Tıp Dergisi, 2020
Larynx cancer (LCa) is the most common malignancy of the head and neck neoplasms accounting for nearly 1% to 2.5% of all human cancers. Almost 95% of these type of cancer originate from squamous cells.
Murat Kaya, Ömer Faruk Karataş
doaj   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

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