Results 271 to 280 of about 360,344 (284)
Some of the next articles are maybe not open access.
2016
MicroRNAs (miRNAs) are small, highly conserved noncoding RNA molecules involved in the regulation of gene expression. Since each miRNA regulates the expression of hundreds of target mRNAs, miRNAs could function as master coordinators, efficiently regulating fundamental cellular processes, including proliferation, apoptosis, and development. Furthermore,
Lu, Gao, Feng, Jiang
openaire +2 more sources
MicroRNAs (miRNAs) are small, highly conserved noncoding RNA molecules involved in the regulation of gene expression. Since each miRNA regulates the expression of hundreds of target mRNAs, miRNAs could function as master coordinators, efficiently regulating fundamental cellular processes, including proliferation, apoptosis, and development. Furthermore,
Lu, Gao, Feng, Jiang
openaire +2 more sources
miRNAs Targeting and Targeting miRNAs
2009With the recent advance of research into microRNAs (miRNAs), this category of endogenous noncoding small ribonucleic acids (19–25 nts in length) has rapidly emerged as one of the central regulators of expression of an extensive repertoire of genes. MiRNAs are an abundant RNA species constituting >2% of the predicted human genes (> 1,000 genes), which ...
openaire +1 more source
Science, 2017
Small RNA Decay Although much work has examined microRNA (miRNA) biogenesis, relatively little is known about miRNA decay. Elbarbary et al. now identify Tudor-SN, an endonuclease that interacts with the RNA-induced silencing complex. Tudor-SN targets miRNAs at CA and UA dinucleotides located more than five nucleotides from miRNA ends. Tudor–SN-mediated
openaire +2 more sources
Small RNA Decay Although much work has examined microRNA (miRNA) biogenesis, relatively little is known about miRNA decay. Elbarbary et al. now identify Tudor-SN, an endonuclease that interacts with the RNA-induced silencing complex. Tudor-SN targets miRNAs at CA and UA dinucleotides located more than five nucleotides from miRNA ends. Tudor–SN-mediated
openaire +2 more sources
Life Sciences, 2011
Despite significant advances in treatments, cardiovascular disease (CVD) remains the leading cause of human morbidity and mortality in developed countries. The development of novel and efficient treatment strategies requires an understanding of the basic molecular mechanisms underlying cardiac function.
Terry S, Elton +5 more
openaire +2 more sources
Despite significant advances in treatments, cardiovascular disease (CVD) remains the leading cause of human morbidity and mortality in developed countries. The development of novel and efficient treatment strategies requires an understanding of the basic molecular mechanisms underlying cardiac function.
Terry S, Elton +5 more
openaire +2 more sources
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
The Epstein-Barr virus (EBV) is an oncogenic Herpes virus involved in the induction of a variety of human tumours. It was the first virus found to encode microRNAs (miRNAs). MiRNAs are short, non-coding RNAs that in most cases negatively regulate gene expression at the post-transcriptional level.
Stephanie, Barth +2 more
openaire +2 more sources
The Epstein-Barr virus (EBV) is an oncogenic Herpes virus involved in the induction of a variety of human tumours. It was the first virus found to encode microRNAs (miRNAs). MiRNAs are short, non-coding RNAs that in most cases negatively regulate gene expression at the post-transcriptional level.
Stephanie, Barth +2 more
openaire +2 more sources
NTP4 modulates miRNA accumulation via asymmetric modification of miRNA/miRNA* duplex
Science China Life Sciences, 2020Wenwen, Kong +7 more
openaire +2 more sources
miRNA Microarray Technology in miRNA Profiling
Current Bioinformatics, 2009Shu-Ting Wang, Cai Li, Lei Liu
openaire +1 more source