Results 21 to 30 of about 25,182 (194)

The role of TDP-43 mislocalization in amyotrophic lateral sclerosis

open access: yesMolecular Neurodegeneration, 2020
Since its discovery as a primary component in cytoplasmic aggregates in post-mortem tissue of patients with Amyotrophic Lateral Sclerosis (ALS), TAR DNA Binding Protein 43 kDa (TDP-43) has remained a central focus to understand the disease.
Terry R. Suk, Maxime W. C. Rousseaux
doaj   +1 more source

Is mislocalization during saccades related to the position of the saccade target within the image or to the gaze position at the end of the saccade? [PDF]

open access: yesPLoS ONE, 2013
A stimulus that is flashed around the time of a saccade tends to be mislocalized in the direction of the saccade target. Our question is whether the mislocalization is related to the position of the saccade target within the image or to the gaze position
Maria Matziridi   +2 more
doaj   +1 more source

Boron deficiency responses in maize (Zea mays L.) roots

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView., 2023
Abstract Background Boron (B) is an essential micronutrient for plants. Dicot plants respond to insufficient B supply by altering root architecture and root hair growth. How root systems of rather low‐B demanding monocot species such as maize (Zea mays L.) respond to B deficiency in terra has not been experimentally resolved, yet.
Manuela Désirée Bienert   +5 more
wiley   +1 more source

Perisaccadic mislocalization without saccadic eye movements [PDF]

open access: yesNeuroscience, 2006
Despite frequent saccadic gaze shifts we perceive the surrounding visual world as stable. It has been proposed that the brain uses extraretinal eye position signals to cancel out saccade-induced retinal image motion. Nevertheless, stimuli flashed briefly around the onset of a saccade are grossly mislocalized, resulting in a shift and, under certain ...
F, Ostendorf   +3 more
openaire   +2 more sources

Mechanisms Underlying Aquaporin-4 Subcellular Mislocalization in Epilepsy

open access: yesFrontiers in Cellular Neuroscience, 2022
Epilepsy is a chronic brain disorder characterized by unprovoked seizures. Mechanisms underlying seizure activity have been intensely investigated.
Jenny I. Szu, Devin K. Binder
doaj   +1 more source

Perisaccadic Mislocalization Orthogonal to Saccade Direction [PDF]

open access: yesNeuron, 2004
Saccadic eye movements transiently distort perceptual space. Visual objects flashed shortly before or during a saccade are mislocalized along the saccade direction, resembling a compression of space around the saccade target. These mislocalizations reflect transient errors of processes that construct spatial stability across eye movements.
Kaiser M, Lappe M
openaire   +3 more sources

Rare missense mutations in ABCA7 might increase Alzheimer’s disease risk by plasma membrane exclusion

open access: yesActa Neuropathologica Communications, 2022
The adenosine triphosphate–binding cassette subfamily A member 7 gene (ABCA7) is associated with Alzheimer’s disease (AD) in large genome-wide association studies.
Liene Bossaerts   +4 more
doaj   +1 more source

Drosophila CG17003/leaky (lky) is required for microtubule acetylation in early germ cells in Drosophila ovary.

open access: yesPLoS ONE, 2022
Microtubule acetylation is found in populations of stable, long-lived microtubules, occurring on the conserved lysine 40 (K40) residue of α-tubulin by α-tubulin acetyltransferases (αTATs).
Matthew Antel   +3 more
doaj   +1 more source

Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation

open access: yesNeurobiology of Disease, 2018
TAR DNA-binding protein 43 (TDP43) plays a significant role in familiar and sporadic amyotrophic lateral sclerosis (ALS). The diverse postulated mechanisms by which TDP43 mutations cause the disease are not fully understood.
N. Kreiter   +10 more
doaj   +1 more source

Visual Mislocalization of Moving Objects in an Audiovisual Event. [PDF]

open access: yesPLoS ONE, 2016
The present study investigated the influence of an auditory tone on the localization of visual objects in the stream/bounce display (SBD). In this display, two identical visual objects move toward each other, overlap, and then return to their original ...
Yousuke Kawachi
doaj   +1 more source

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