Results 41 to 50 of about 32,684 (231)

Reduced Gene Dosage of Histone H4 Prevents CENP-A Mislocalization and Chromosomal Instability in Saccharomyces cerevisiae.

open access: yesGenetics, 2021
Mislocalization of the centromeric histone H3 variant (Cse4 in budding yeast, CID in flies, CENP-A in humans) to non-centromeric regions contributes to chromosomal instability (CIN) in yeast, fly, and human cells.
Jessica R. Eisenstatt   +8 more
semanticscholar   +1 more source

Rare missense mutations in ABCA7 might increase Alzheimer’s disease risk by plasma membrane exclusion

open access: yesActa Neuropathologica Communications, 2022
The adenosine triphosphate–binding cassette subfamily A member 7 gene (ABCA7) is associated with Alzheimer’s disease (AD) in large genome-wide association studies.
Liene Bossaerts   +4 more
doaj   +1 more source

Perisaccadic mislocalization without saccadic eye movements [PDF]

open access: yesNeuroscience, 2006
Despite frequent saccadic gaze shifts we perceive the surrounding visual world as stable. It has been proposed that the brain uses extraretinal eye position signals to cancel out saccade-induced retinal image motion. Nevertheless, stimuli flashed briefly around the onset of a saccade are grossly mislocalized, resulting in a shift and, under certain ...
F, Ostendorf   +3 more
openaire   +2 more sources

Perisaccadic Mislocalization Orthogonal to Saccade Direction [PDF]

open access: yesNeuron, 2004
Saccadic eye movements transiently distort perceptual space. Visual objects flashed shortly before or during a saccade are mislocalized along the saccade direction, resembling a compression of space around the saccade target. These mislocalizations reflect transient errors of processes that construct spatial stability across eye movements.
Kaiser M, Lappe M
openaire   +3 more sources

Drosophila CG17003/leaky (lky) is required for microtubule acetylation in early germ cells in Drosophila ovary.

open access: yesPLoS ONE, 2022
Microtubule acetylation is found in populations of stable, long-lived microtubules, occurring on the conserved lysine 40 (K40) residue of α-tubulin by α-tubulin acetyltransferases (αTATs).
Matthew Antel   +3 more
doaj   +1 more source

Visual Mislocalization of Moving Objects in an Audiovisual Event. [PDF]

open access: yesPLoS ONE, 2016
The present study investigated the influence of an auditory tone on the localization of visual objects in the stream/bounce display (SBD). In this display, two identical visual objects move toward each other, overlap, and then return to their original ...
Yousuke Kawachi
doaj   +1 more source

Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation

open access: yesNeurobiology of Disease, 2018
TAR DNA-binding protein 43 (TDP43) plays a significant role in familiar and sporadic amyotrophic lateral sclerosis (ALS). The diverse postulated mechanisms by which TDP43 mutations cause the disease are not fully understood.
N. Kreiter   +10 more
doaj   +1 more source

Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis

open access: yesBrain : a journal of neurology, 2019
See Vidal and Atkin (doi:10.1093/brain/awz256) for a scientific commentary on this article. ALS remains incurable due to an incomplete understanding of its molecular pathogenesis. Tyzack, Luisier et al.
Giulia E. Tyzack   +11 more
semanticscholar   +1 more source

RNA-binding protein altered expression and mislocalization in MS

open access: yesNeurology: Neuroimmunology & Neuroinflammation, 2020
Objective To determine whether there are nuclear depletion and cellular mislocalization of RNA-binding proteins (RBPs) transactivation response DNA-binding protein of 43 kDa (TDP-43), fused in sarcoma (FUS), and polypyrimidine tract–binding protein (PTB)
K. Masaki   +10 more
semanticscholar   +1 more source

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