Results 31 to 40 of about 32,684 (231)
bioRxiv, 2021 Variants within the UNC13A gene have long been known to increase risk of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two related neurodegenerative diseases defined by mislocalization of the RNA-binding protein TDP-43.
Anna L. Brown +22 more
semanticscholar +1 more source
Nucleolar stress in C9orf72 and sporadic ALS spinal motor neurons precedes TDP-43 mislocalization
Acta Neuropathologica Communications, 2021 Nucleolar stress has been implicated in the pathology and disease pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) from repeat expansions of GGGGCC in C9orf72 (C9-ALS/FTLD) but not in sporadic ALS (SALS ...
O. Aladesuyi Arogundade +5 more
semanticscholar +1 more source
Brain Communications, 2021 RNA binding proteins have been shown to play a key role in the pathogenesis of amyotrophic lateral sclerosis (ALS). Mutations in valosin-containing protein (VCP/p97) cause ALS and exhibit the hallmark nuclear-to-cytoplasmic mislocalization of RNA binding
Jasmine Harley +3 more
semanticscholar +1 more source
Mislocalization after inhibition of saccadic adaptation
Journal of Vision, 2022 Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
Heins, Frauke, Lappe, Markus
openaire +3 more sources
Translational Neurodegeneration, 2021 Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective, early degeneration of motor neurons in the brain and spinal cord.
F. Theunissen +7 more
semanticscholar +1 more source
Brain Sciences, 2021 Multiple sclerosis (MS) is an inflammatory disease of the central nervous system with a significant neurodegenerative component. Dysfunctional RNA-binding proteins (RBPs) are causally linked to neuronal damage and are a feature of MS, including the ...
Muxue Li +3 more
doaj +1 more source
Visual mislocalization during saccade sequences [PDF]
Experimental Brain Research, 2014 Visual objects briefly presented around the time of saccadic eye movements are perceived compressed towards the saccade target. Here, we investigated perisaccadic mislocalization with a double-step saccade paradigm, measuring localization of small probe dots briefly flashed at various times around the sequence of the two saccades. At onset of the first
Eckart Zimmermann +2 more
openaire +3 more sources
Journal of Neuropathology and Experimental Neurology, 2021 Abnormal protein accumulation and mislocalization is a general hallmark of Alzheimer disease. Recent data suggest nucleocytoplasmic transport may be compromised by tau in Alzheimer disease.
J. Dickson +3 more
semanticscholar +1 more source
Boron deficiency responses in maize (Zea mays L.) roots
Journal of Plant Nutrition and Soil Science, EarlyView., 2023 Abstract Background Boron (B) is an essential micronutrient for plants. Dicot plants respond to insufficient B supply by altering root architecture and root hair growth. How root systems of rather low‐B demanding monocot species such as maize (Zea mays L.) respond to B deficiency in terra has not been experimentally resolved, yet.
Manuela Désirée Bienert +5 more
wiley +1 more source
Is mislocalization during saccades related to the position of the saccade target within the image or to the gaze position at the end of the saccade? [PDF]
PLoS ONE, 2013 A stimulus that is flashed around the time of a saccade tends to be mislocalized in the direction of the saccade target. Our question is whether the mislocalization is related to the position of the saccade target within the image or to the gaze position
Maria Matziridi +2 more
doaj +1 more source