Results 91 to 100 of about 151,537 (305)

Pembrolizumab Activity in Recurrent High-Grade Gliomas with Partial or Complete Loss of Mismatch Repair Protein Expression: A Monocentric, Observational and Prospective Pilot Study [PDF]

, 2020
Pembrolizumab demonstrated promising results in hypermutated tumors of diverse origin. Immunohistochemical loss of mismatch repair (MMR) proteins has been suggested as a surrogate of hypermutation in high-grade gliomas (HGG).
Maria Caffo, Franco Chioffi, Susanna Mandruzzato, Fassan, Matteo, Gardiman, Marina Paola, Marco Pizzi, Mandruzzato, Susanna, Arianna Fassina, Marta Padovan, Caccese, Mario, Vittorina Zagonel, Masetto, Elena, Scarpa, Aldo, Elena Masetto, Maria Giuseppina Bonavina, Angelo Paolo Dei Tos, Fassina, Arianna, Dei Tos, Angelo Paolo, Giuseppe Lombardi, Luca Denaro, Simonelli, Matteo, Bonavina, Maria Giuseppina, Persico, Pasquale, Matteo Fassan, Valeria Barresi, Pasquale Persico, Barresi, Valeria, Pizzi, Marco, Indraccolo, Stefano, Stefano Indraccolo, Aldo Scarpa, Michele Simbolo, Marina Paola Gardiman, Denaro, Luca, Matteo Simonelli, Padovan, Marta, Simbolo, Michele, Caffo, Maria, Chioffi, Franco, Mario Caccese, Zagonel, Vittorina, Lombardi, Giuseppe   +41 more
core   +1 more source

Thermally Pre‐Formed Reconfigurable Resistive Random‐Access Memory Crossbar Arrays: A Dual‐Mode Platform for Robust Physically Unclonable Functions and In‐Memory Computing

Advanced Functional Materials, EarlyView.
A reconfigurable RRAM platform utilizing thermally pre‐formed filaments (TPFs) is developed to realize robust hardware security. By exploiting the thermodynamic stochasticity of TPFs, exceptionally reliable physically unclonable functions (PUFs) are achieved.
Seongbin Kwon, Taewon Lee, Dohyeong Kim, Sungmin Hwang, Sungjoon Kim   +4 more
wiley   +1 more source

Evaluating the impact of donor eGFR and HLA-DR mismatch on graft survival in living donor kidney transplants

Frontiers in Nephrology
BackgroundThis study assesses the impact of human leukocyte antigen (HLA)-DR mismatch and donor-estimated glomerular filtration rate (eGFR) on outcomes of living donor kidney transplantation (LDKT), which are especially relevant to the availability of ...
Pooja Budhiraja, Jesse D. Schold, Jesse D. Schold, Rocio Lopez, Rocio Lopez, Susana Arrigain, Susana Arrigain, Bruce Kaplan, Bruce Kaplan   +8 more
doaj   +1 more source

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry [PDF]

, 2012
Debate continues as to the usefulness of assessing adenomas for loss of mismatch repair protein expression to identify individuals with suspected Lynch syndrome. We tested 109 polyps from 69 proven mutation carriers (35 females and 34 males) belonging to
Hopper, John L., Arnold, ST, Spring, K., Ahnen, D., Thibodeau, S., Pearson, SA, Suthers, G., Pavluk, E, Walker, Neal I., Pavluk, Erika, Clendenning, M, Parry, Susan, Baron, J., Thidodeau, Stephen N., Hopper, John L, Hopper, J., Ahnen, DJ, Young, JP, Jenkins, M., Baron, John A., Baron, John A, Win, A., Thibodeau, SN, Spring, Kevin J. (R17176), Lindor, Noralane, Arnold, Sven T., Baron, JA, Pavluk, E., Goldblatt, Jack, Walsh, Michael D., Jenkins, MA, Glendenning, Mark, Win, Aung Ko, Phillips, Kerry, et al., Walters, Rhiannon J, Walsh, Michael D, Thibodeau, Stephen N., Jenkins, Mark A., Buchanan, DD, Goldblatt, J, Jass, JR, Buchanan, Daniel D., Suthers, Graeme K., Walsh, M., Goldblatt, J., Hopper, JL, Spring, Kevin J., Buchanan, Daniel D, Spring, Kevin J, Walker, NI, Clendenning, Mark, Nagler, B, Win, AK, Jenkins, Mark A, Walters, RJ, Walsh, MD, Clendenning, M., Thibodeau, Stephen N, Pearson, S., Jass, Jeremy R., Jass, Jeremy R, Ahnen, Dennis J, Walker, Neal I, George, Jill, Spring, KJ, Young, Joanne P, Ahnen, Dennis J., Suthers, Graeme K, Lindor, N, Arnold, S., Phillips, K., Nagler, Belinda, George, J, Suthers, GK, Walters, Rhiannon J., Arnold, Sven T, Jass, J., Parry, S, Phillips, K, Nagler, B., Rosty, Christophe, George, J., Pearson, Sally-Ann, Young, Joanne P., Buchanan, D., Walters, R., Rosty, C   +87 more
core   +2 more sources

Bandgap‐Engineered AlGaAs/GaAs Heterostructures for Wavelength‐Selective Dual‐Polarity Photoelectrochemistry

Advanced Functional Materials, EarlyView.
Bandgap‐engineered AlGaAs/GaAs heterostructures exhibit wavelength‐selective dual‐polarity photoelectrochemistry, switching from photocathodic to photoanodic response depending on excitation wavelength. The polarity transition is governed by band‐selective absorption, built‐in electric‐field‐driven carrier transport, and interfacial charge‐transfer ...
Yukai Mao, Lipin Chen, Jules Courtin, Siyu Lin, Gangri Cai, Yan Zhu, Yoan Léger, Nicolas Bertru, Jinshi Zhao, Charles Cornet   +9 more
wiley   +1 more source

Bridging Radiology and Pathology: ATRX Loss and T2-FLAIR Mismatch as Early Diagnostic and Prognostic Markers in Diffuse Gliomas

Journal of the Pakistan Medical Association
ATRX mutation and the T2-FLAIR mismatch sign haveemerged as complementary molecular and imagingmarkers in diffuse gliomas. ATRX loss defines IDH-mutantastrocytoma at the molecular level, while the mismatchsign provides a non-invasive radiological clue ...
Quratulain Tariq, Eisha Abid Ali, Rahamah Arshad, Ahmad Sohail, Irfan Yousaf, Muhammad Shahzad Shamim   +5 more
doaj   +1 more source

Heterogenous mismatch-repair status in colorectal cancer [PDF]

, 2014
Background: Immunohistochemical staining for mismatch repair proteins is efficient and widely used to identify mismatch repair defective tumors. The tumors typically show uniform and widespread loss of MMR protein staining.
Nynke Veurink, Nilbert, Mef, Harbo, Maria, Louise Klarskov, Mef Nilbert, Bojesen, Anders, Holck, Susanne, Joost, Patrick, Rambech, Eva,, Baldetorp, Bo, Rambech, Eva, Joost, Patrick,, Maria Harbo, Bo Baldetorp, Eva Rambech, Patrick Joost, Klarskov, Louise, Lund University., Susanne Holck, Anders Bojesen, Veurink, Nynke, Baldetorp, Bo,, Nilbert, Mef,   +22 more
core   +1 more source

Shaping Matter with Acoustic Waves: From Particles to Functional Structures

Advanced Functional Materials, EarlyView.
Acoustic‐directed assembly is reviewed as a materials‐oriented strategy for organizing particles, polymers, metals, and biological systems into functional structures. The review distinguishes reversible manipulation from permanent structure formation through medium fixation, particle fixation, and in situ material generation, highlighting routes toward
Avraham Kenigsberg, Shelly Zlotnikov, Maya Fiorentino, Yuval Elias, Ornit Nagler‐Avramovitz, Hagay Shpaisman   +5 more
wiley   +1 more source

Supplementary Table S1 from Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment [PDF]

, 2007
Supplementary Table S1 from Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide ...
Linsey B. Reavie (14979597), Candice A. Romany (14979594), Tracy T. Batchelor (14879504), William T. Curry (10666911), Kymberly K. Levine (14879501), P. Andrew Futreal (8980754), David N. Louis (14871071), Daniel P. Cahill (5693057), Rebecca A. Betensky (11771969), Patrick J. Codd (14979591), Michael R. Stratton (9682037), A. John Iafrate (8756931)   +11 more
core   +1 more source

Synthesis of AgBiS2 and AgInS2 Based on Formation Energies in Sulfur‐Rich Reducing Flame

Advanced Functional Materials, EarlyView.
High‐surface‐area AgInS2 and AgBiS2 nanoparticles were synthesized via enclosed flame spray pyrolysis by tuning flame conditions and formation energies to guide phase formation. Flame parameters were tuned to suppress oxides and enable pure sulfide phase growth.
Muhammad Ali Martuza, Marco Schowalter, Andreas Rosenauer, Olga V. Kuharenko, Christian Rossner, Johannes Birkenstock, Lutz Mädler, Suman Pokhrel   +7 more
wiley   +1 more source