Results 11 to 20 of about 66,055 (244)
Jixie chuandong, 2023 A method for designing tooth surface of spiral bevel gears based on quantitative mismatch modification is proposed in this study. Firstly, the mathematical relationship between modification quantity, modification coefficient and structural parameters of ...
Geng Longlong, Nie Shaowu, Jiang Chuang
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Improved strategy for mutation detection—a modification to the enzyme mismatch cleavage method
Nucleic Acids Research, 1995 Jeffrey Babon +2 more
exaly +4 more sources
Frontiers in Molecular Biosciences, 2022 Background: Bladder cancer (BLCA) is one of the most common cancer types worldwide. The disease is responsible for about 200,000 deaths annually, thus improved diagnostics and therapy is needed.
Zhangli Su +10 more
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Nature Communications, 2021 m6A RNA post-transcriptional modification changes RNA hybridization kinetics. Here the authors show that the methylamino group can adopt syn-conformation pairing with uridine with a mismatch-like conformation in RNA duplex.
Bei Liu +8 more
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Allele-Specific PCR for PIK3CA Mutation Detection Using Phosphoryl Guanidine Modified Primers
Diagnostics, 2023 Phosphoryl guanidine (PG) is the novel uncharged modification of internucleotide phosphates of oligonucleotides. Incorporating PG modification into PCR primers leads to increased discrimination between wild-type and mutated DNA, providing extraordinary ...
Alexey S. Chubarov +5 more
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Regulation of mismatch repair by histone code and posttranslational modifications in eukaryotic cells [PDF]
DNA Repair, 2016 DNA mismatch repair (MMR) protects genome integrity by correcting DNA replication-associated mispairs, modulating DNA damage-induced cell cycle checkpoints and regulating homeologous recombination. Loss of MMR function leads to cancer development. This review describes progress in understanding how MMR is carried out in the context of chromatin and how
Feng, Li +3 more
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Dynamics of a DNA Mismatch Site Held in Confinement Discriminate Epigenetic Modifications of Cytosine [PDF]
Journal of the American Chemical Society, 2017 The identification and discrimination of four epigenetic modifications to cytosine in the proposed active demethylation cycle is demonstrated at the single-molecule level, without the need for chemical pretreatment or labeling. The wild-type protein nanopore α-hemolysin is used to capture individual DNA duplexes containing a single cytosine-cytosine ...
Robert P. Johnson +4 more
openaire +3 more sources
High-precision mapping reveals rare N 6 -deoxyadenosine methylation in the mammalian genome
Cell Discovery, 2022 N 6-deoxyadenosine methylation (6mA) is the most widespread type of DNA modification in prokaryotes and is also abundantly distributed in some unicellular eukaryotes. However, 6mA levels are remarkably low in mammals.
Li-Qian Chen +12 more
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Haematologica, 2021 HLA-DPB1 mismatches between donor and recipient are commonly seen in allogeneic hematopoietic stem cell transplantation from an unrelated donor. HLA-DPB1 mismatch, conventionally determined by the similarity of the T-cell epitope (TCE), is associated ...
Jun Zou +16 more
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Optimizing the face Paradigm of BCI system by modified Mismatch Negative paradigm
Frontiers in Neuroscience, 2016 Many recent studies have focused on improving the performance of event-related potential (ERP) based brain computer interfaces (BCIs). The use of a face pattern has been shown to obtain high classification accuracies and information transfer rates (ITRs)
Siejie Zhou, Jing Jin, Wang Xingyu
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