, 2018 Tumor hypoxia is associated with radioresistance and poor prognosis after radiation therapy for prostate cancer (PCa). In this prospective pilot study, we assessed the ability of 18F-misonidazole (18F-MISO) positron emission tomography (PET)-magnetic ...
Valentina Garibotto +15 more
core +1 more source
Low-Energy Electron Induced Reactions in Metronidazole at Different Solvation Conditions. [PDF]
Pharmaceuticals (Basel), 2022 Lochmann C +6 more
europepmc +1 more source
Improving Tumor Hypoxia Location in 18F-Misonidazole PET with Dynamic Contrast-enhanced MRI Using Quantitative Electron Paramagnetic Resonance Partial Oxygen Pressure Images. [PDF]
Radiol Imaging Cancer, 2021 Gertsenshteyn I +18 more
europepmc +1 more source
The effect of misonidazole on cell survival at low doses of radiation
, 1983 Since Puck and Marcus first measured the effect of ionizing radiation on mammalian cell survival in 1956 the 'Puck plating' assay has been widely used as an endpoint for radiobiology experiments.
Faddegon, Bruce Alan
core
Lymphocyte Infiltration Determines the Hypoxia-Dependent Response to Definitive Chemoradiation in Head-and-Neck Cancer: Results from a Prospective Imaging Trial. [PDF]
J Nucl Med, 2021 Nicolay NH +9 more
europepmc +1 more source
Response of human tumour xenografts to fractionated X-irradiation.
, 1986 The response of two human tumour xenografts to single dose and fractionated X-rays has been tested using regrowth delay as the assay. The tumours were line transplanted cells from a moderately well-differentiated squamous carcinoma of the tonsillar fossa
Hermeking, H. +3 more
core +1 more source
Functionalized Nitroimidazole Scaffold Construction and Their Pharmaceutical Applications: A 1950-2021 Comprehensive Overview. [PDF]
Pharmaceuticals (Basel), 2022 Gupta R +5 more
europepmc +1 more source
Walsh & Hoyt: Miscellaneous Drugs
, 2005 Laetrile. Misonidazole. Allopurinol. Retinoids. Topoisomerase inhibitors. Amsacrine. Camptothecin. Epipodophyllotoxin VP-16 (etoposide). Epipodophyllotoxin VM-26 (teniposide). Irinotecan (Camptosar). Topotecan (Hycamtin). Thalidomide.
Mark L. Moster, MD; Rod Foroozan, MD
core
Design, Synthesis and Anticancer Evaluation of Nitroimidazole Radiosensitisers. [PDF]
Molecules, 2023 Liew LP +6 more
europepmc +1 more source
Oxygen effect for double-strand break induction determined by pulsed-field gel electrophoresis.
, 1992 The induction of DNA double-strand breaks (dsb) following irradiation under oxygenated and hypoxic conditions with and without misonidazole was measured by pulsed-field gel electrophoresis (PFGE) in a human bladder carcinoma cell line.
Whitaker, Stephen J. +1 more
core