In Vivo Evaluation of the Nitroimidazole‐Based Thioflavin‐T Derivatives as Cerebral Ischemia Markers
International Journal of Biomedical Imaging, Volume 2007, Issue 1, 2007., 2007 Timely imaging and accurate interpretation of cerebral ischemia are required to identify patients who might benefit from more aggressive therapy, and nuclear medicine offers a noninvasive method for demonstrating cerebral ischemia. Three nitroimidazole‐based thioflavin‐T derivatives, N‐[4‐(benzothiazol‐2‐yl)phenyl]‐3‐(4‐nitroimidazole‐1‐yl) propanamide
Taiwei Chu +4 more
wiley +1 more source
Focal Spot, Spring/Summer 1980 [PDF]
, 1980 https://digitalcommons.wustl.edu/focal_spot_archives/1026/thumbnail ...
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Comparison of chemical clustering methods using graph- and fingerprint-based similarity measures [PDF]
, 2003 This paper compares several published methods for clustering chemical structures, using both graph- and fingerprint-based similarity measures. The clusterings from each method were compared to determine the degree of cluster overlap. Each method was also
Blankley, C.J. +2 more
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Focal Spot, Fall/Winter 1980 [PDF]
, 1980 https://digitalcommons.wustl.edu/focal_spot_archives/1027/thumbnail ...
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Effect of misonidazole on neurotransmitter systems
International Journal of Radiation Oncology*Biology*Physics, 1986 This study examines the effect of chronic administration of misonidazole on four neurotransmitter pathways (norepinephrine, dopamine, acetylcholine, and GABA) of the central nervous system (CNS). Biochemical assays examined the neurotransmitter synthesizing enzymes tyrosine hydroxylase (TOH) for catecholamines and choline acetyltransferase (CAT) for ...
T H, McNeill +4 more
openaire +2 more sources
MR imaging features of high-grade gliomas in murine models: How they compare with human disease, reflect tumor biology, and play a role in preclinical trials [PDF]
, 2011 Murine models are the most commonly used and best investigated among the animal models of HGG. They constitute an important weapon in the development and testing of new anticancer drugs and have long been used in preclinical trials. Neuroimaging methods,
Borges, A. R. +3 more
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High resolution PET, SPECT and projection imaging in small animals [PDF]
, 2001 Positron emission tomography, single photon emission computed tomography and planar projection imaging of radioactive tracers have long been in use for detecting and diagnosing disease in human subjects.
Eckelman, William C. +5 more
core +2 more sources
Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation [PDF]
, 2017 Background: Hypoxia-induced radioresistance constitutes a major obstacle for a curative treatment of cancer. The aim of this study was to investigate effects of photon and carbon ion irradiation in combination with inhibitors of DNA-Damage Response (DDR)
Abdollahi, Amir +12 more
core +2 more sources
216 Jewish Hospital of St. Louis [PDF]
, 1982 https://digitalcommons.wustl.edu/bjc_216/1159/thumbnail ...
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