Hypoxia in Head and Neck Squamous Cell Carcinoma
International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012 Hypoxia is a common feature in most of the solid tumors including head and neck squamous cell carcinoma (HNSCC). Hypoxia reflects the imbalance between oxygen consumption by the rapidly proliferating cancer cells and the insufficient oxygen delivery due to poor vascularization and blood supply.
John Zenghong Li +6 more
wiley +1 more source
Journal of Chemistry, Volume 8, Issue 3, Page 1120-1123, 2011., 2011 In the present study we report the synthesis and antibacterial activity of a new series 2‐(1‐methyl‐4‐nitro‐1H‐imidazol‐5‐ylsulfonyl)‐1,3,4‐thiadiazoles (6a-c). Compounds 6a-c were tested in vitro by the conventional agar dilution method against a panel of microorganisms including gram‐negative and gram‐positive bacteria.
Bahram Letafat +3 more
wiley +1 more source
Cancer Science, Volume 115, Issue 1, Page 227-236, January 2024.Quantitative non‐hypoxic (Splatoon) maps of the tumors tested. The Splatoon maps indicate accelerated tumor reoxygenation in the tumors irradiated with neon ions. Abstract Charged particle beams induce various biological effects by creating high‐density ionization through the deposition of energy along the beam's trajectory.
Akiko Imaizumi +5 more
wiley +1 more source
Recent Advances in Image‐Guided Radiotherapy for Head and Neck Carcinoma
Journal of Oncology, Volume 2009, Issue 1, 2009., 2009 Radiotherapy has a well‐established role in the management of head and neck cancers. Over the past decade, a variety of new imaging modalities have been incorporated into the radiotherapy planning and delivery process. These technologies are collectively referred to as image‐guided radiotherapy and may lead to significant gains in tumor control and ...
Sameer K. Nath +4 more
wiley +1 more source
Effect of misonidazole on neurotransmitter systems
International Journal of Radiation Oncology*Biology*Physics, 1986 This study examines the effect of chronic administration of misonidazole on four neurotransmitter pathways (norepinephrine, dopamine, acetylcholine, and GABA) of the central nervous system (CNS). Biochemical assays examined the neurotransmitter synthesizing enzymes tyrosine hydroxylase (TOH) for catecholamines and choline acetyltransferase (CAT) for ...
T H, McNeill +4 more
openaire +2 more sources
The Therapeutic Potential of Imidazole or Quinone-Based Compounds as Radiosensitisers in Combination with Radiotherapy for the Treatment of Head and Neck Squamous Cell Carcinoma. [PDF]
Cancers (Basel), 2022 Azad A, Kong A.
europepmc +1 more source
Low-Energy Electron Induced Reactions in Metronidazole at Different Solvation Conditions. [PDF]
Pharmaceuticals (Basel), 2022 Lochmann C +6 more
europepmc +1 more source
Improving Tumor Hypoxia Location in 18F-Misonidazole PET with Dynamic Contrast-enhanced MRI Using Quantitative Electron Paramagnetic Resonance Partial Oxygen Pressure Images. [PDF]
Radiol Imaging Cancer, 2021 Gertsenshteyn I +18 more
europepmc +1 more source
Lymphocyte Infiltration Determines the Hypoxia-Dependent Response to Definitive Chemoradiation in Head-and-Neck Cancer: Results from a Prospective Imaging Trial. [PDF]
J Nucl Med, 2021 Nicolay NH +9 more
europepmc +1 more source
Functionalized Nitroimidazole Scaffold Construction and Their Pharmaceutical Applications: A 1950-2021 Comprehensive Overview. [PDF]
Pharmaceuticals (Basel), 2022 Gupta R +5 more
europepmc +1 more source