Results 231 to 240 of about 216,996 (340)

Comparative effects of platelets and plasma-derived mitochondria in early-phase Achilles tendon inflammation. [PDF]

Regen Biomater
Kim SH, Back ES, Lim M, Kim MJ, Yun CK, Choi YS.   +5 more
europepmc   +1 more source

Responsive nanoheterojunctions for built‐in electric field‐promoted cascade tumor targeting and cuproptosis‐based therapy

Responsive Materials, EarlyView.
Nanoheterojunctions have been synthesized as responsive biomaterials for cascade targeting of tumor cells and mitochondria, ROS‐mediated apoptosis and Cu‐promoted cuproptosis. And drug‐device‐field integration as an advanced paradigm of tumor treatment was employed for photo‐triggered tumor cell elimination in vitro and lesion eradication in vivo ...
Zhe Liu, Yandai Lin, Xuehui Li, Fengqi Xuan   +3 more
wiley   +1 more source

Dysregulation of autophagosome-mitochondria contacts contributes to autophagy dysfunction and neurodegeneration in tauopathy. [PDF]

Proc Natl Acad Sci U S A
Jia N, Guan H, Zuo Y, Jeong YY, Amireddy N, Rajapaksha G, Gonzalez CU, Jaber N, Lee YK, Nissenbaum M, Margolis DJ, Dai W, Kusnecov AW, Cai Q.   +13 more
europepmc   +1 more source

A lysosome‐targeted ultra‐sensitive viscosity probe for monitoring viscosity alterations during chemotherapy

Smart Molecules, EarlyView.
A novel chemosensing platform based on a molecular rotor architecture is established for specific, dynamic detection of lysosomal viscosity. The platform allows real‐time tracking of lysosomal viscosity fluctuations induced by various chemotherapeutic agents, highlighting its significant potential as a powerful tool for early cancer diagnostics and ...
Haoyang Song, Hui Bian, Lei Liu, Gahyeon Park, Bingqing Sun, Qiongzheng Hu, Juyoung Yoon   +6 more
wiley   +1 more source

A photoimmune synergizing RNA interference technology for highly effective antitumor treatment

Smart Molecules, EarlyView.
We developed a red‐light‐activated small‐molecule photosensitizer FNBS, which enables simultaneous photodynamic immunotherapy and RNA interference. FNBS can induce pyroptosis, immunogenic cell death and RNA degradation, avoiding the carrier‐dependent delivery drawbacks of conventional RNAi therapy, converting cold tumors into hot tumors and ...
Xiang Xia, Bingbing Wu, Xueze Zhao, Wen Sun, Jianjun Du, Jiangli Fan, Xiaojun Peng   +6 more
wiley   +1 more source

Adipose-cartilage communication via EV-Mito-mtDNA signaling promotes osteoarthritis progression. [PDF]

Sci Adv
Gu C, Liao F, Kong G, Yin S, Jiang Y, Zhou R, Zeng J, Wu Y, Li X, Wang B, Pang Q, Fu M, Zhu Q, Zheng C.   +13 more
europepmc   +1 more source

Differentiating high‐ and low‐grade serous ovarian carcinoma using radiomics: a pilot study

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To identify ultrasound‐based radiomics features capable of distinguishing between high‐grade serous ovarian carcinomas (HGSC) and invasive low‐grade serous ovarian carcinomas (LGSC), and to develop machine‐learning models that include radiomics features to discriminate between the two.
F. Ciccarone, G. Zinicola, E. H. Tran, G. Baldassari, E. Boccia, C. Nero, F. Moro, T. Pasciuto, G. Scambia, G. Ferrandina, A. Fagotti, A. C. Testa, D. Lorusso, Collaborators, F. Borella, F. Buonomo, R. Fruscio, F. Pozzati   +17 more
wiley   +1 more source

Transplantation of AQP1-overexpressing mitochondria attenuates periodontitis-associated bone loss by regulating mitochondria-ER contacts of macrophages. [PDF]

J Nanobiotechnology
Yang S, Zhang M, Wei J, Yu L, Li H, Rong S, Chen L, Zhao T, Zhan J, Wang X, Xie Y, Wang Y.   +11 more
europepmc   +1 more source

“Women of the Happy Life”: Prostitution, Public Morality, and Venereal Disease in US‐Occupied Nicaragua, 1912–33

Gender &History, EarlyView.
ABSTRACT During the years of the US occupation (1912–33), Nicaragua's government legally regulated prostitution. Convinced of their objectives to protect society's moral and public health, politicians embarked on a long struggle to apprehend, quarantine, and segregate female prostitutes nationwide.
Eimeel Castillo
wiley   +1 more source

Transient ultrasonographic findings suggestive of vesicoureteral reflux associated with cystitis in pediatric and adolescent patients: Case reports and pathophysiological insights. [PDF]

Radiol Case Rep
Homma R, Yanai T, Motoyama K, Saito H, Izumi I.   +4 more
europepmc   +1 more source