Results 251 to 260 of about 618,328 (350)

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

MitoTracker transfers from astrocytes to neurons independently of mitochondria. [PDF]

Cell Rep Methods
Hole KL, Norkett R, Russell E, Cottilli P, Strom M, Howden JH, Corbett NJ, Brownlees J, Devine MJ.   +8 more
europepmc   +1 more source

Re‐Evaluating Hot Mitochondria: Too Slow to Cool

Acta Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Aim Mito Thermo Yellow (MTY) is a mitochondrially targeted fluorophore that shows marked fluorescence quenching with increasing temperature, allowing for interrogating temperature dynamics in the mitochondria of live cells. Here we re‐evaluate published MTY fluorescence responses used to argue in favor of the ‘hot mitochondria’ concept; the ...
Jason R. Treberg, Ryan J. Mailloux
wiley   +1 more source

Pathogenic roles of the IMNEPD-associated PTRH2 mutants in aggravating mitochondrial dynamics and its rescue. [PDF]

Mol Med
Na D, Yoo S, Jeong M, Lee N, Kim Y, Kim Y, Cho DH, Jung YK.   +7 more
europepmc   +1 more source

Los medios argentinos frente a la muerte de Diana de Gales. Análisis de la construcción sensacionalista de un mito de fin de siglo

, 2005
María Verónica Crespi
openalex   +2 more sources

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, Volume 183, Issue 9, Page 1939-1957, May 2026.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Plasmodium falciparum stomatin-like protein forms a putative complex with a metalloprotease in distinct mitochondrial loci. [PDF]

PLoS Pathog
Verhoef JMJ, Bekkering ET, Boshoven C, Hannon M, Evers F, Proellochs NI, Spruijt CG, Kooij TWA.   +7 more
europepmc   +1 more source

El mito euskera

Publicat a El Periódico.
openaire   +2 more sources

Ageing‐Dependent Thyroid Hormone Receptor α Reduction Activates IP3R1‐Meditated Ca2+ Transfer in MAM and Exacerbates Skeletal Muscle Atrophy in Mice

Cell Proliferation, Volume 59, Issue 5, May 2026.
During skeletal muscle ageing, down‐regulation of TRα expression activates IP3R1 transcriptional expression, promotes MAM calcium transport, triggers mitochondrial calcium overload and apoptosis, leading to skeletal muscle atrophy. Restoring TRα expression can improve IP3R1‐mediated mitochondrial calcium overload and apoptosis in ageing skeletal muscle
Runqing Shi, Yusheng Zhang, Gong Chen, Jiru Zhang, Jing Liu, Hao Zhu, Minne Sun, Yu Duan   +7 more
wiley   +1 more source