Results 261 to 270 of about 216,996 (340)

Budding speciation, mitochondrial capture and introgression between surface and cave lineages in the Asellus aquaticus species complex

Cladistics, EarlyView.
Abstract Replicated pairs of ancestral and evolutionarily derived populations provide opportunities to test hypotheses about the deterministic laws of evolution. The Asellus aquaticus species complex is an invertebrate model system with several independent surface‐to‐cave transitions and a complicated and unresolved evolutionary history.
Peter Trontelj, Valerija Zakšek, Anja Palandačić, Hans Recknagel   +3 more
wiley   +1 more source

Echoes in the powerhouse: mito-lncRNAs contribution to cardiac function and disease. [PDF]

Acta Pharmacol Sin
Chaurembo AI, Xing N, Huang ZF, Mayamba BS, Chanda F, Liang YT, Lin YF, Deng WH, Huang JY, He ZY, Tan Z, Shu C, Lin HB.   +12 more
europepmc   +1 more source

Testing the morphology‐ and intuition‐based taxonomic hypotheses using integrative approach: unexpected discovery of triplet of sibling species within a widespread Eurasian butterfly, Hyponephele lycaon

Cladistics, EarlyView.
Abstract In well‐studied groups of organisms, the taxonomic landscape can be very complex, with several alternative classifications describing diversity within the same set of populations. For example, three hypotheses have previously been proposed to describe the taxonomy of the common and widespread Eurasian Dusky Meadow Brown butterfly, Hyponephele ...
Elena A. Pazhenkova, Vladimir A. Lukhtanov   +1 more
wiley   +1 more source

Mitochondrial translation termination, recycling, reinitiation, and rescue for in-frame and out-of-frame contexts. [PDF]

Nat Commun
Wakigawa T, Mito M, Fang Q, Itoh Y, Shinkai Y, Iwasaki S.   +5 more
europepmc   +1 more source

Oxidative Stress Drives Cell Cycle Stalling, Apoptosis and Metabolic Suppression in Cystatin B Deficient EPM1 Patient iPSCs

Cell Proliferation, EarlyView.
CSTB deficient EPM1 iPS cells manifest increased lysosomal activity and oxidative stress, which lead to DNA damage, cell cycle defects and increased apoptosis. As a protective response, metabolism is suppressed. Image created by BioRender https://BioRender.com/t44oc6h.
Shekhar Singh, Lidiia Plotnikova, Teemu Tiukuvaara, Reetta Kälviäinen, Riikka H. Hämäläinen   +4 more
wiley   +1 more source

Image-enabled cell sorting permits prospective isolation of primitive hematopoietic stem cell subsets with distinct functional potential.

Exp Hematol
Cabrera-Cosme L, Bennett E, Miłek J, Albakova Z, Hogg AJ, Davies SJ, Mann SK, Hogg K, O'Toole P, Kent DG.   +9 more
europepmc   +1 more source

Small extracellular vesicle signaling and mitochondrial transfer reprogram T helper cell function in human asthma. [PDF]

Nat Commun
Hough KP, Trevor JL, Ahmad S, Wang Y, Chacko BK, Goliwas KF, Strenkowski JG, Liu Y, Nowak JI, Becker EJ, Kim YI, Holmes R, Bone NB, Vang S, Pritchard A, Chin J, Bodduluri S, Antony VB, Tousif S, Athar M, Chanda D, Mitra K, Zmijewski JW, Zhang J, Duncan SR, Thannickal VJ, Gabrielsson S, Darley-Usmar VM, Deshane JS.   +28 more
europepmc   +1 more source

A 3D Bioprinted Platform That Maintains the Functional Integrity of Primary AML Cells

Cell Proliferation, EarlyView.
This study presents a 3D bioprinted platform using gelatin‐hyaluronic acid hydrogels to enhance primary AML cell survival and proliferation while preserving stem‐like properties in vitro. By recapitulating in vivo‐like metabolic activity and drug resistance, this system offers a robust tool for preclinical drug screening and personalised therapy ...
Wanling Huang, Bo Deng, Nini Guo, Yiyi Ding, Zhangjingwen Xu, Yiwen Lu, Yue Ma, Qian Ren, Nan Wang, Pengyu Huang, Xiaotong Ma   +10 more
wiley   +1 more source

Mitochondria-lysosome coupling contributes to lysosome acidification and aging. [PDF]

Mol Cell
Liu Q, Yoo S, Zhang ZA, Li L, Su H, Vannur L, Wooldredge AC, Hughes JB, Desprez PY, Hao N, Lithgow G, Andersen JK, Hansen M, Campisi J, Zhou C.   +14 more
europepmc   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

Cell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo, Xiaoya Zhang, Danmei Zhang, Chunxia Shi, Luwen Wang, Zuojiong Gong   +5 more
wiley   +1 more source