Results 191 to 200 of about 156,228 (267)

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Intramyocellular lipid droplet-mitochondria uncoupling drives muscle atrophy via metabolite-directed epigenetic reprogramming: a review. [PDF]

Front Endocrinol (Lausanne)
Wu L, Wang Y, Ma K, Liu Y.
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Mitochondrial Dysfunction in Type 2 Diabetes and Metabolic Syndrome: Mechanisms, Biomarkers, and Emerging Therapies. [PDF]

Diabetes Metab Syndr Obes
Alghzawi HM, Younas S, Sahu S, Farooq S, Nafees M, Mohammed S.   +5 more
europepmc   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Preserved mitochondrial respiration in presence of oxidative stress and reduced mitochondrial mass after 10-day bed rest in older adults. [PDF]

J Physiol
Motanova E, Zuccarelli L, Lysenko E, Amoretti S, Pirazzini M, Rossetto O, Brocca L, Bottinelli R, Pellegrino MA, Baldassarre G, Gissi C, Lippe G, Gasparini M, Šimunic B, Pišot R, Grassi B, Narici MV.   +16 more
europepmc   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Micro-CT reconstruction and structural morphology of the alimentary canal in adult <i>Tomicus yunnanensis</i> (Coleoptera: Curculionidae: Scolytinae). [PDF]

Front Physiol
Wang Y, Tang X, Dong S, Li Z.
europepmc   +1 more source

Uncovering cardiac molecular remodelling in racing Thoroughbreds with paroxysmal atrial fibrillation

Equine Veterinary Journal, EarlyView.
Abstract Background Atrial fibrillation (AF) is the most common arrhythmia in both humans and horses, with a comparable prevalence of ~2%. In horses, AF is a major cause of poor athletic performance and linked to sudden cardiac death, yet its underlying molecular mechanisms remain poorly understood.
Charlotte E. Edling, Magdalena Arevalo‐Turrubiarte, Carla Moller‐Levet, Bronte Forbes, Victoria Kemp, Joe Weir, Gary Tse, Celia Marr, Rebecca Lewis, Kamalan Jeevaratnam   +9 more
wiley   +1 more source

Metabolic Malfunction Mars Muscle Mitochondria

Neurology Genetics
Guido Primiano, Ian Holt
openaire   +2 more sources