Results 141 to 150 of about 698,916 (379)

Bisphenol S induces brown adipose tissue whitening and aggravates diet-induced obesity in an estrogen-dependent manner

Cell Reports, 2023
Summary: Bisphenol S (BPS) exposure has been implied epidemiologically to increase obesity risk, but the underlying mechanism is unclear. Here, we propose that BPS exposure at an environmentally relevant dose aggravates diet-induced obesity in female ...
Xue Wen, Yang Xiao, Haitao Xiao, Xueqin Tan, Beiyi Wu, Zehua Li, Ru Wang, Xuewen Xu, Tao Li   +8 more
doaj  

THE INTERNAL ORGANIZATION OF MITOCHONDRIA [PDF]

, 1956
E. L. Powers, C. F. Ehret, L. E. Roth, O. T. Minick   +3 more
openalex   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Protein phosphatase 2Cm-regulated branched-chain amino acid catabolic defect in dorsal root ganglion neurons drives pain sensitization

Acta Neuropathologica Communications
Maladaptive changes of metabolic patterns in the lumbar dorsal root ganglion (DRG) are critical for nociceptive hypersensitivity genesis. The accumulation of branched-chain amino acids (BCAAs) in DRG has been implicated in mechanical allodynia and ...
Nan Lian, Fangzhou Li, Cheng Zhou, Yan Yin, Yi Kang, Kaiteng Luo, Su Lui, Tao Li, Peilin Lu   +8 more
doaj   +1 more source

Hypoxic acclimation improves cardiac redox homeostasis and protects heart against ischemia-reperfusion injury through upregulation of O-GlcNAcylation

Redox Biology, 2021
Ischemia-reperfusion (I/R) injury is detrimental to cardiovascular system. Alteration in glucose metabolism has been recognized as an important adaptive response under hypoxic conditions.
Wei Ou, Yu Liang, Yu Qin, Wei Wu, Maodi Xie, Yabing Zhang, Yarong Zhang, Liwei Ji, Haiyang Yu, Tao Li   +9 more
doaj  

Photostimulation activates restorable fragmentation of single mitochondrion by initiating oxide flashes [PDF]

arXiv, 2015
Mitochondrial research is important to ageing, apoptosis, and mitochondrial diseases. In previous works, mitochondria are usually stimulated indirectly by proapoptotic drugs to study mitochondrial development, which is in lack of controllability, or spatial and temporal resolution.
arxiv  

SOME PERMEABILITY PROPERTIES OF ISOLATED RAT LIVER CELL MITOCHONDRIA [PDF]

, 1956
Kenneth L. Jackson, Nello Pace
openalex   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Mitochondrial energy metabolism in diabetic cardiomyopathy: Physiological adaption, pathogenesis, and therapeutic targets

Chinese Medical Journal
. Diabetic cardiomyopathy is defined as abnormal structure and function of the heart in the setting of diabetes, which could eventually develop heart failure and leads to the death of the patients.
Wanlin Ye, Kun Han, Maodi Xie, Sheyu Li, Guo Chen, Yanyan Wang, Tao Li, Jinjiao Li   +7 more
doaj   +1 more source

Dual effects of bisphenol A on wound healing, involvement of estrogen receptor β

Ecotoxicology and Environmental Safety, 2022
Bisphenol A (BPA) is a ubiquitous environmental pollutant that can specifically induce estrogen receptor β (ERβ) expression, and the latter plays a crucial role during wound healing. However, no study has investigated the association between BPA exposure
Xue Wen, Man Zhu, Zehua Li, Tao Li, Xuewen Xu   +4 more
doaj