Results 251 to 260 of about 1,007,169 (424)

Improved Efficacy of Triple‐Negative Breast Cancer Immunotherapy via Hydrogel‐Based Co‐Delivery of CAR‐T Cells and Mitophagy Agonist

open access: yesAdvanced Science, EarlyView.
Trop2‐targeted CAR‐T cells experienced reduced efficacy and functional exhaustion at a low E:T ratio caused by mitophagy‐mediated mitochondrial dysfunction. Next, the mitophagy is screened agonist BC1618, which significantly strengthened the antitumor response of CAR‐T cells via improving the level of mitophagy, suggesting a promising approach to ...
Guodong Li   +11 more
wiley   +1 more source

Mitochondria transplantation transiently rescues cerebellar neurodegeneration improving mitochondrial function and reducing mitophagy in mice. [PDF]

open access: yesNat Commun
Li SJ   +12 more
europepmc   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

open access: yesAdvanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng   +8 more
wiley   +1 more source

PHOSPHORYLATIVE AND NONPHOSPHORYLATIVE PATHWAYS OF ELECTRON TRANSFER IN RAT LIVER MITOCHONDRIA

open access: green, 1956
Nathan O. Kaplan   +3 more
openalex   +1 more source

3‐D Sustained‐Release Culture Carrier Alleviates Rat Intervertebral Disc Degeneration by Targeting STING in Transplanted Skeletal Stem Cells

open access: yesAdvanced Science, EarlyView.
Schematic representation of mechanisms by which the 3‐D sustained‐release culture carrier prevents accumulation of ROS by continuously releasing C‐176@PDA‐NPs and inhibiting the cGAS‐STING activated by sudden hypoxia, thereby preventing ferroptosis and promoting differentiation in SSCs and ultimately attenuating IVDD progression.
Liwen Luo   +12 more
wiley   +1 more source

Therapeutic mitochondria treatment amplifies macrophage-mediated phagocytosis and recycling exocytosis. [PDF]

open access: yesJ Cereb Blood Flow Metab
Tanaka M   +10 more
europepmc   +1 more source

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