Results 301 to 310 of about 1,007,169 (424)

Some chemical components of mitochondria and microsomes from germinating castor beans [PDF]

, 1957
Takashi Akazawa, Harry Beevers
openalex   +1 more source

Targeting USP1 Potentiates Radiation‐Induced Type I IFN‐Dependent Antitumor Immunity by Enhancing Oligo‐Ubiquitinated SAR1A‐Mediated STING Trafficking and Activation

Advanced Science, EarlyView.
Targeting USP1 is identified as a strategy that significantly enhances type I IFN‐dependent innate immune response within the TME following radiotherapy. Mechanistically, USP1 inhibition facilitates STING trafficking from ER to Golgi by preserving K27‐linked oligo‐ubiquitination of SAR1A, thereby facilitating efficient activation of the dsDNA‐cGAS ...
Weilin Zhou, Yuxuan Zhao, Wenjing Qin, Weijian Wu, Chenyang Liao, Yiqiu Zhang, Xingli Yang, Xue Chen, Youqiao Wang, Yushan Kang, Jiaxin Wu, Jiaojiao Zhao, Junmin Quan, Xuecen Wang, Xianzhang Bu, Xin Yue   +15 more
wiley   +1 more source

Functional Nucleic Acid Nanostructures for Mitochondrial Targeting: The Basis of Customized Treatment Strategies. [PDF]

Molecules
He W, Dong S, Zeng Q.
europepmc   +1 more source

Cytological Fixation of Mitochondria by Acids [PDF]

, 1954
W. G. Bruce Casselman, Barbara M. Jordan
openalex   +1 more source

Enhancing Osteogenesis through Bio‐Inspired Recombinant Coral Protein Galaxin by Targeting Mitochondrial Metabolism and ATP Production

Advanced Science, EarlyView.
The study highlights the potential of recombinant galaxin (a coral protein) as a novel and effective biomaterial for bone regeneration. It binds to ATP synthase subunit β (ATP5B) in mouse pre‐osteoblasts, thereby causing increased ATP production and mitochondrial activity.
Fei Yu, Xing Zhao, Ting Jiang, Ningjuan Ouyang, Peilin Li, Wei Yang, Zhihe Zhao   +6 more
wiley   +1 more source

Multiple Inhibitory Mechanisms of DS16570511 Targeting Mitochondrial Calcium Uptake: Insights from Biochemical Analysis of Rat Liver Mitochondria. [PDF]

Int J Mol Sci
Yamada A, Watanabe A, Nara A, Inokuma T, Asano M, Shinohara Y, Yamamoto T.   +6 more
europepmc   +1 more source

Targeting Histone Deacetylase 11 with a Highly Selective Inhibitor for the Treatment of MASLD

Advanced Science, EarlyView.
A potent HDAC11‐specific inhibitor, B6, is identified using substrate‐mimic and bioisosteric replacement strategies. B6 demonstrates high oral bioavailability, extensive liver distribution, and a favorable safety profile. B6 effectively alleviates metabolic dysfunction‐associated steatotic liver disease by increasing the expression of LKB1 and ...
Feng Zhang, Kairui Yue, Simin Sun, Shengyuan Lu, Geng Jia, Yang Zha, Shuang Zhang, C. James Chou, Chenzhong Liao, Xiaoyang Li, Yajun Duan   +10 more
wiley   +1 more source

The Intersection of Mitophagy and Autism Spectrum Disorder: A Systematic Review. [PDF]

Int J Mol Sci
Kovacheva E, Gevezova M, Mehterov N, Kazakova M, Sarafian V.   +4 more
europepmc   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

Advanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He, Siliang Chen, Xiaoyun Wang, Xiang Wen, Changyang Gong, Lei Liu, Gu He   +6 more
wiley   +1 more source

DeepCristae, a CNN for the restoration of mitochondria cristae in live microscopy images. [PDF]

Commun Biol
Papereux S, Leconte L, Valades-Cruz CA, Liu T, Dumont J, Chen Z, Salamero J, Kervrann C, Badoual A.   +8 more
europepmc   +1 more source