Results 301 to 310 of about 916,375 (359)

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Human midbrain organoids reveal the characteristics of axonal mitochondria specific to dopaminergic neurons. [PDF]

Mol Brain
Nishijima A, Yokota M, Kakuta S, Yamaguchi A, Ishikawa KI, Okano H, Akamatsu W, Hattori N, Koike M.   +8 more
europepmc   +1 more source

MDP25‐VDAC3 Complex Orchestrates Actin Remodeling and Mitochondrial Dynamics to Modulate Innate Immunity in Arabidopsis

Advanced Science, EarlyView.
This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou, Pengfei Lu, Xuan Cui, Liangfeng Luo, Qing Pan, Jiejie Li   +5 more
wiley   +1 more source

Editorial to the special issue on extracellular vesicles and mitochondria in CNS function and disease. [PDF]

J Cereb Blood Flow Metab
Hayakawa K, Hermann DM.
europepmc   +1 more source

Targeting VCP with V8 suppresses glioblastoma development via formation of aggregates and disruption of mitophagy flux. [PDF]

Cell Oncol (Dordr)
Cao X, Li Y, Guo B, Liu Y, Wang B, Wang H, Lu J, Wei L, Gao Y, Guo Y, Wu T.   +10 more
europepmc   +1 more source

Prokaryotic organelle mitochondria drive tumorigenesis: "the original sin". [PDF]

Front Oncol
Wang C, Luo M, Zhou J, Zhang Q, Ji X, He J, Wang L, Huang Y, Xue X, Wang F.   +9 more
europepmc   +1 more source

The pivotal role of mitochondria in osteoporosis: From pathogenesis to future therapies. [PDF]

Biochem Biophys Rep
Shi C, Chen L, Li J, Shi T, Yang C, Zhao L.   +5 more
europepmc   +1 more source

Exploiting Cancer Cell Mitochondria as a Therapeutic Strategy: Structure Activity Relationship Analysis of Synthetic Analogues of Pancratistatin

, 2016
Dennis Ma
openalex   +1 more source