Results 71 to 80 of about 1,007,169 (424)
Aberrant branched-chain amino acid catabolism in cardiovascular diseases
Frontiers in Cardiovascular Medicine, 2022 Globally, cardiovascular diseases are the leading cause of death. Research has focused on the metabolism of carbohydrates, fatty acids, and amino acids to improve the prognosis of cardiovascular diseases.
Yixiao Xiong +5 more
doaj +1 more source
Mitochondria and Neurodegeneration
Bioscience Reports, 2007 Many lines of evidence suggest that mitochondria have a central role in ageing-related neurodegenerative diseases. However, despite the evidence of morphological, biochemical and molecular abnormalities in mitochondria in various tissues of patients with neurodegenerative disorders, the question “is mitochondrial dysfunction a necessary step in ...
PETROZZI, LUCIA +4 more
openaire +4 more sources
Dynamic Metabolic Response to Adriamycin-Induced Senescence in Breast Cancer Cells
Metabolites, 2018 Cellular senescence displays a heterogeneous set of phenotypes linked to tumor suppression; however, after drug treatment, senescence may also be involved in stable or recurrent cancer. Metabolic changes during senescence can provide detailed information
Rong You +4 more
doaj +1 more source
Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation [PDF]
, 2016 Mitochondria-associated membranes (MAMs) are subdomains of the endoplasmic reticulum (ER) that interact with mitochondria. This membrane scrambling between ER and mitochondria appears to play a critical role in the earliest steps of autophagy.
Faggioni, Alberto +9 more
core +2 more sources
Cancers, 2020 Mitochondria are indispensable for energy metabolism and are essential for the regulation of many cellular processes in healthy as well as in transformed cells [...]
openaire +3 more sources
Molecules, 2023 Astragalus alcohol soluble polysaccharide (AASP) could present superior water solubility and antitumor activity with high concentration. Selenium nanoparticles (SeNPs) have received growing attention in various fields, but their unstable property ...
Haiyu Ji +5 more
doaj +1 more source
Active thermodynamic force driven mitochondrial alignment [PDF]
arXiv, 2023 Mitochondria are critical organelles in eukaryotes that produce the energy currency ATP. In nerve axons, mitochondria are known to align at almost regular intervals to maintain a constant ATP concentration, but little is known about the mechanism. In this letter, we show theoretically that ATP production and ATP-dependent non-directional movement of ...
arxiv
Analysis of two genomes from the mitochondrion-like organelle of the intestinal parasite Blastocystis: complete sequences, gene content, and genome organization. [PDF]
, 2008 Acquisition of mitochondria by the ancestor of all living eukaryotes represented a crucial milestone in the evolution of the eukaryotic cell. Nevertheless, a number of anaerobic unicellular eukaryotes have secondarily discarded certain mitochondrial ...
Clark, C Graham, Pérez-Brocal, Vicente
core +2 more sources
Piperine Derivatives Enhance Fusion and Axonal Transport of Mitochondria by Activating Mitofusins
Chemistry, 2022 Piperine (1-piperoylpiperidine) is the major pungent component of black pepper (Piper nigrum) and exhibits a spectrum of pharmacological activities. The molecular bases for many of piperine’s biological effects are incompletely defined. We noted that the
Lihong Zhang +4 more
doaj +1 more source
Advanced Deep Networks for 3D Mitochondria Instance Segmentation [PDF]
arXiv, 2021 Mitochondria instance segmentation from electron microscopy (EM) images has seen notable progress since the introduction of deep learning methods. In this paper, we propose two advanced deep networks, named Res-UNet-R and Res-UNet-H, for 3D mitochondria instance segmentation from Rat and Human samples.
arxiv