Results 91 to 100 of about 250,267 (298)

Genome Rearrangement in Mitochondria and Its Computational Biology

, 2005
In the first part of this paper, we investigate gene orders of closely related mitochondrial genomes for studying the properties of mutations rearranging genes in mitochondria. Our conclusions are that the evolution of mitochondrial genomes is more complicated than it is considered in recent methods, and stochastic modelling is necessary for its deeper
Miklos, I, Hein, J
openaire   +2 more sources

Global analyses of Ceratocystis cacaofunesta mitochondria: from genome to proteome [PDF]

BMC Genomics, 2013
Abstract Background The ascomycete fungus Ceratocystis cacaofunesta is the causal agent of wilt disease in cacao, which results in significant economic losses in the affected producing areas. Despite the economic importance of the Ceratocystis complex of species, no genomic data are available for any of its members ...
Ambrosio, Alinne Batista, do Nascimento, Leandro Costa, Oliveira, Bruno V, L Teixeira, Paulo José P, Tiburcio, Ricardo A, Toledo Thomazella, Daniela P, Leme, Adriana F P, Carazzolle, Marcelo F, Vidal, Ramon O, Mieczkowski, Piotr, Meinhardt, Lyndel W, Pereira, Gonçalo A G, Cabrera, Odalys G   +12 more
openaire   +2 more sources

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]

, 2019
Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico, Bertoli, Alessandro, Buson, Lisa, Cagnin, Stefano, Chemello, Francesco, Grespi, Francesca, Lanfranchi, Gerolamo, Martini, Paolo, Massimino, Maria L, Millino, Caterina, Pacchioni, Beniamina, Peggion, Caterina, Romualdi, Chiara, Scorrano, Luca   +13 more
core   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Enzymes involved in organellar DNA replication in photosynthetic eukaryotes

Frontiers in Plant Science, 2014
Plastids and mitochondria possess their own genomes. Although the replication mechanisms of these organellar genomes remain unclear in photosynthetic eukaryotes, several organelle-localized enzymes related to genome replication, including DNA polymerase,
Takashi eMoriyama, Takashi eMoriyama, Naoki eSato, Naoki eSato   +3 more
doaj   +1 more source

A simplified method to isolate rice mitochondria

Plant Methods, 2020
Background Mitochondria play critical roles in plant growth, development and stress tolerance. Numerous researchers have carried out studies on the plant mitochondrial genome structure, mitochondrial metabolism and nuclear-cytoplasmic interactions ...
Yanghong Xu, Xiaoyi Li, Jishuai Huang, Leilei Peng, Dinghui Luo, Qiannan Zhang, Zhiwu Dan, Haijun Xiao, Fang Yang, Jun Hu   +9 more
doaj   +1 more source

Organellar carbon metabolism is co-ordinated with distinct developmental phases of secondary xylem [PDF]

, 2019
Subcellular compartmentation of plant biosynthetic pathways in the mitochondria and plastids requires coordinated regulation of nuclear encoded genes, and the role of these genes has been largely ignored by wood researchers. In this study, we constructed
Fierro Gutierrez, Ana Carolina Elisa, Marchal, Kathleen, Mizrachi, Eshchar, Myburg, Alexander A, Pinard, Desré   +4 more
core   +2 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Bioenergetics Consequences of Mitochondrial Transplantation in Cardiomyocytes. [PDF]

, 2020
Background Mitochondrial transplantation has been recently explored for treatment of very ill cardiac patients. However, little is known about the intracellular consequences of mitochondrial transplantation.
Ali Pour, Paria, Kenney, M Cristina, Kheradvar, Arash   +2 more
core