Results 11 to 20 of about 533,276 (294)

Mitochondria as a Target for Future Diabetes Treatments

International Journal of Medical Students, 2015
Diabetes mellitus is rapidly becoming the world’s most dangerous serial killer. Type 1 diabetes (T1D) is a currently incurable autoimmune disease marked by progressive, and eventually exhaustive, destruction of the insulin-producing pancreatic beta cells.
Franziska Thimm, Marten Szibor
doaj   +3 more sources

Anesthetic considerations of Joubert syndrome in patients with mitochondrial disease - A case report - [PDF]

Anesthesia and Pain Medicine, 2021
Background Joubert syndrome and mitochondrial disease are rare congenital diseases in which a wide range of symptoms affects multiple organs. Patients with these diseases present characteristic symptoms related to the musculoskeletal, respiratory, and ...
Jeong Yeon Kim, Koun Jeong, Ki Seob Han, Ji Eun Park, Mun Gyu Kim, Mi Roung Jun   +5 more
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Morning and evening exercise

Integrative Medicine Research, 2013
A growing body of evidence suggests that exercise may contribute to preventing pathological changes, treating multiple chronic diseases, and reducing mortality and morbidity ratios.
Dae Yun Seo, SungRyul Lee, Nari Kim, Kyung Soo Ko, Byoung Doo Rhee, Byung Joo Park, Jin Han   +6 more
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Mitochondrial Disease and Stroke [PDF]

Stroke, 2001
It is well known that some mitochondrial disorders are responsible for ischemic cerebral infarction in young patients. Our purpose was to determine, in this prospective ongoing study, whether ischemic stroke is the only manifestation of a mitochondrial disorder in young patients.Patients aged
E, Martínez-Fernández, A, Gil-Peralta, R, García-Lozano, I, Chinchón, I, Aguilera, O, Fernández-López, J, Arenas, Y, Campos, J, Bautista   +8 more
openaire   +2 more sources

Pu-18-N-butylimide-NMGA-GNP conjugate is effective against hepatocellular carcinoma

Integrative Medicine Research, 2013
Background: Photodynamic therapy (PDT) is a new modality in the treatment of cancer. This study thus aims to examine whether the PDT is effective against in vivo hepatocellular carcinoma.
Jin-Geun Kwon, In-Sung Song, Min-Soo Kim, Beom Hee Lee, Jung Hwa Kim, Il Yoon, Young Key Shim, Nari Kim, Jin Han, Jae Boum Youm   +9 more
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Acetylcholinesterase Inhibitory Activity of Pigment Echinochrome A from Sea Urchin Scaphechinus mirabilis

Marine Drugs, 2014
Echinochrome A (EchA) is a dark-red pigment of the polyhydroxynaphthoquinone class isolated from sea urchin Scaphechinus mirabilis. Acetylcholinesterase (AChE) inhibitors are used in the treatment of various neuromuscular disorders, and are considered as
Sung Ryul Lee, Julius Ryan D. Pronto, Bolor-Erdene Sarankhuu, Kyung Soo Ko, Byoung Doo Rhee, Nari Kim, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Jin Han   +9 more
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E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages

Bioengineering & Translational Medicine, 2021
Recent studies indicate that umbilical cord stem cells are cytoprotective against several disorders. One critical limitation in using stem cells is reduction in their viability under stressful conditions, such as diabetes.
Ayaz Ali, Wei‐Wen Kuo, Chia‐Hua Kuo, Jeng‐Fan Lo, Michael Y. C. Chen, Jayasimha R. Daddam, Tsung‐Jung Ho, Vijaya Padma Viswanadha, Marthandam Asokan Shibu, Chih‐Yang Huang   +9 more
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Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs

Marine Drugs, 2014
Echinochrome A (Ech A) is a naphthoquinoid pigment from sea urchins that possesses antioxidant, antimicrobial, anti-inflammatory and chelating abilities.
Seung Hun Jeong, Hyoung Kyu Kim, In-Sung Song, Seon Joong Lee, Kyung Soo Ko, Byoung Doo Rhee, Nari Kim, Natalia P. Mishchenko, Sergey A. Fedoryev, Valentin A. Stonik, Jin Han   +10 more
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Echinochrome A Increases Mitochondrial Mass and Function by Modulating Mitochondrial Biogenesis Regulatory Genes

Marine Drugs, 2014
Echinochrome A (Ech A) is a natural pigment from sea urchins that has been reported to have antioxidant properties and a cardio protective effect against ischemia reperfusion injury.
Seung Hun Jeong, Hyoung Kyu Kim, In-Sung Song, Su Jin Noh, Jubert Marquez, Kyung Soo Ko, Byoung Doo Rhee, Nari Kim, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Jin Han   +11 more
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Quality Matters? The Involvement of Mitochondrial Quality Control in Cardiovascular Disease

Frontiers in Cell and Developmental Biology, 2021
Cardiovascular diseases are one of the leading causes of death and global health problems worldwide. Multiple factors are known to affect the cardiovascular system from lifestyles, genes, underlying comorbidities, and age.
Kai-Lieh Lin, Kai-Lieh Lin, Shang-Der Chen, Shang-Der Chen, Shang-Der Chen, Kai-Jung Lin, Chia-Wei Liou, Chia-Wei Liou, Chia-Wei Liou, Yao-Chung Chuang, Yao-Chung Chuang, Yao-Chung Chuang, Pei-Wen Wang, Pei-Wen Wang, Jiin-Haur Chuang, Jiin-Haur Chuang, Tsu-Kung Lin, Tsu-Kung Lin, Tsu-Kung Lin   +18 more
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