Results 41 to 50 of about 10,242,723 (401)
Indicators of mitochondrial disease [PDF]
Sao Paulo Medical Journal, 2013 In the article, the authors hypothesize that hepatosteatosis with unknown etiology presented by group of pediat-ric patients may be mitochondrial disease. They attribute their idea to mitochondrial structural abnormalities detected through electron microscopy examination.
Kurt, Yasemin Gulcan +3 more
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Mitochondria as a Target for Future Diabetes Treatments
International Journal of Medical Students, 2015 Diabetes mellitus is rapidly becoming the world’s most dangerous serial killer. Type 1 diabetes (T1D) is a currently incurable autoimmune disease marked by progressive, and eventually exhaustive, destruction of the insulin-producing pancreatic beta cells.
Franziska Thimm, Marten Szibor
doaj +3 more sources
Anesthetic considerations of Joubert syndrome in patients with mitochondrial disease - A case report - [PDF]
Anesthesia and Pain Medicine, 2021 Background Joubert syndrome and mitochondrial disease are rare congenital diseases in which a wide range of symptoms affects multiple organs. Patients with these diseases present characteristic symptoms related to the musculoskeletal, respiratory, and ...
Jeong Yeon Kim +5 more
doaj +1 more source
Mitochondrial Dynamics in Mitochondrial Diseases
Diseases, 2016 Mitochondria are very versatile organelles in continuous fusion and fission processes in response to various cellular signals. Mitochondrial dynamics, including mitochondrial fission/fusion, movements and turnover, are essential for the mitochondrial network quality control.
Juan Suárez-Rivero +9 more
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Mitochondrial heterogeneity in diseases
Signal Transduction and Targeted Therapy, 2023 AbstractAs key organelles involved in cellular metabolism, mitochondria frequently undergo adaptive changes in morphology, components and functions in response to various environmental stresses and cellular demands. Previous studies of mitochondria research have gradually evolved, from focusing on morphological change analysis to systematic multiomics,
Long Chen +8 more
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Integrative Medicine Research, 2013 A growing body of evidence suggests that exercise may contribute to preventing pathological changes, treating multiple chronic diseases, and reducing mortality and morbidity ratios.
Dae Yun Seo +6 more
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Ophthalmoplegia in Mitochondrial Disease [PDF]
Yonsei Medical Journal, 2018 To evaluate the classification, diagnosis, and natural course of ophthalmoplegia associated with mitochondrial disease.Among 372 patients with mitochondrial disease who visited our hospital between January 2006 and January 2016, 21 patients with ophthalmoplegia were retrospectively identified.
Ji Hoon Na +4 more
openaire +3 more sources
OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability. [PDF]
, 2012 BackgroundMitochondrial fusion protein mutations are a cause of inherited neuropathies such as Charcot-Marie-Tooth disease and dominant optic atrophy.
Bers, Donald M +10 more
core +2 more sources
Mitochondrial TCA cycle metabolites control physiology and disease
Nature Communications, 2020 Mitochondria are signaling organelles that regulate a wide variety of cellular functions and can dictate cell fate. Multiple mechanisms contribute to communicate mitochondrial fitness to the rest of the cell.
I. Martínez-Reyes, N. Chandel
semanticscholar +1 more source
Pu-18-N-butylimide-NMGA-GNP conjugate is effective against hepatocellular carcinoma
Integrative Medicine Research, 2013 Background: Photodynamic therapy (PDT) is a new modality in the treatment of cancer. This study thus aims to examine whether the PDT is effective against in vivo hepatocellular carcinoma.
Jin-Geun Kwon +9 more
doaj +1 more source