Results 211 to 220 of about 920,301 (294)

Exploring rare mitochondrial DNA in Leber hereditary optic neuropathy. [PDF]

Adv Ophthalmol Pract Res
Cao S, Liu Y, Sun M, Zhang Y, Sun Y, Xu Q, Wei S, Zhou H.   +7 more
europepmc   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Circulating Serum Cell-Free Mitochondrial DNA in Amyotrophic Lateral Sclerosis. [PDF]

Cells
Zanini G, Martinelli I, Sinigaglia G, Zucchi E, Banchelli F, Simonini C, Gianferrari G, Ghezzi A, Mandrioli J, Pinti M.   +9 more
europepmc   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Mitochondrial DNA and the largest nuclear-mitochondrial DNA in Arabidopsis can be separated by their methylation levels. [PDF]

Plant Physiol
Zhong Y, Okuno M, Tsutsumi N, Arimura SI.   +3 more
europepmc   +1 more source

Heteroplasmy Benchmark Dataset - mitochondrial DNA mixture model - MiSeq - U5-H1-M1-M2-M3-M4-M5 - FASTQ

, 2020
Federica Fazzini, Liane Fendt, Lukas Forer, Jamie Lee Losso, Sebastian Schönherr, Gertraud Streiter, Bernd Schöpf, Anita Kloss‐Brandstätter, Florian Kronenberg, Hansi Weißensteiner   +9 more
openalex   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

Siblings of FBXL4-related mitochondrial DNA depletion syndrome, leading to fatal fulminant pneumonia. [PDF]

Mol Genet Metab Rep
Akiba T, Shimada S, Matsuda S, Ishida S, Baba Y, Yamashita A, Shoji H, Okazaki Y, Murayama K.   +8 more
europepmc   +1 more source

Functional Impact of Nth-like DNA glycosylase on Mitochondrial Dynamics [PDF]

Lisa Hubers, Alexander Myr Sjetne, Luisa Luna, Ane Marit Wågbø, Yohan Lefol, Francisco José Naranjo-Galindo, Anders Knoph Berg-Eriksen, Torkild Visnes, Hilde Nilsen, Nicola P. Montaldo   +9 more
openalex   +1 more source

Mitochondrial DNA: Rearranging the plant genome [PDF]

, 1986
Ronald A. Butow
openalex   +1 more source