Results 231 to 240 of about 582,066 (267)
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MITOCHONDRIAL DNA AND HUMAN EVOLUTION

Annual Review of Genomics and Human Genetics, 2005
▪ Abstract  Several unique properties of human mitochondrial DNA (mtDNA), including its high copy number, maternal inheritance, lack of recombination, and high mutation rate, have made it the molecule of choice for studies of human population history and evolution.
Pakendorf, Brigitte, Stoneking, Mark
openaire   +4 more sources

DISEASES OF THE MITOCHONDRIAL DNA

Annual Review of Biochemistry, 1992
INTRODUCTION . . _ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 175 THE HUMAN MITOCHONDRIAL DNA AND OXIDATIVE PHOSPHORYLATION 1176 Mitochondrial Biogenesis ... 1 176 Mitochondrial OXPHOS Complexes and their Synthesis 1 178 Developmental Regulation of Nuclear OXPHOS Genes ...
openaire   +2 more sources

Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

Genes, Chromosomes and Cancer, 2006
AbstractSomatic mutations in mitochondrial DNA (mtDNA) have been demonstrated in various tumors, including breast cancer. However, it still remains unclear whether the alterations in mtDNA are related to the clinicopathological features and/or the prognosis in the breast cancer.
Ling-Ming, Tseng   +7 more
openaire   +2 more sources

Origin And Evolution Of Mitochondrial DNA

Annual Review of Cell and Developmental Biology, 1989
Devant la diversite en taille, structure, organisation et mode d'expression du DNA mitochondrial, une mise a jour des dernieres hypotheses sur l'origine et l'evolution de ce genome est ...
openaire   +2 more sources

Mitochondrial DNA and disease

The Lancet, 1999
P F, Chinnery, D M, Turnbull
openaire   +2 more sources

Notch3 and mitochondrial DNA

Journal of Molecular Medicine, 2001
Kazuo Ohashi, Frank Park, F.C. Luft
openaire   +2 more sources

Therapeutics and DNA Methylation Inhibitors

Medical Epigenetics, 2021
Shyamala C Navada
exaly  

ASTENOZOOSPERMY AND MITOCHONDRIAL DNA

2006
Male infertility, inability to fecundate the oocyte, is due to alterations of sperm characteristics (low number, low motility, altered morphology), to the quantity of semen or to the presence of alterations in the male genital line. 75% of infertile men deal with untreatable sub-fertility.
CARRA, Elena   +2 more
openaire   +2 more sources

Mitochondrial disease and mitochondrial DNA.

British journal of hospital medicine, 1991
In the last decade there have been dramatic advances in the understanding of genetic, biochemical and clinical aspects of disorders of the mitochondrial respiratory chain. Neurological manifestations are prominent although involvement of other systems is increasingly recognized. This article reviews current understanding of mitochondrial disease and in
S R, Hammans, A E, Harding
openaire   +1 more source

Circulating Tumor DNA in Advanced Solid Tumors: Clinical Relevance and Future Directions

Ca-A Cancer Journal for Clinicians, 2021
Heather Parsons   +2 more
exaly  

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