Results 221 to 230 of about 659,761 (294)

Spatial Patterning of Modular Gelatin‐Peroxide Microspheres in Melt‐Electrowritten Scaffolds Provides Controlled Oxygen Generation and Mitigates Hypoxia and Cytotoxicity

open access: yesAdvanced Healthcare Materials, EarlyView.
A bioassembly approach is described using photo‐crosslinked gelatin‐based microgels containing calcium peroxide (CaO2) to generate oxygen (O2) and enhance cell survival in hypoxic conditions (1% O2). Bioassembly enables spatial patterning of individual CaO2‐laden and mesenchymal stem cell (MSC)‐laden microgels and allows for decoupling and mitigating ...
Axel E. Norberg   +5 more
wiley   +1 more source

Alternative start codon selection shapes mitochondrial function and rare human diseases. [PDF]

open access: yesMol Cell
Ly J   +7 more
europepmc   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

open access: yesAdvanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner   +8 more
wiley   +1 more source

Glucosylsphingosine affects mitochondrial function in a neuronal cell model. [PDF]

open access: yesCommun Biol
Nikolaenko V   +6 more
europepmc   +1 more source

Evaluation of Unsaponifiable Fraction of Avocado Oil on Liver and Kidney Mitochondrial Function in Rats Fed a High-Fat and High-Carbohydrate Diet [PDF]

open access: gold
Marcela González-Montoya   +9 more
openalex   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

open access: yesAdvanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao   +6 more
wiley   +1 more source

CISD2 ensures adequate ER-mitochondrial coupling, critically supporting mitochondrial function in neurons. [PDF]

open access: yesActa Neuropathol Commun
Loncke J   +12 more
europepmc   +1 more source

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