Results 211 to 220 of about 690,576 (265)
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Journal of Laboratory and Clinical Medicine, 2003
Over the past several decades, it has become widely recognized that the mitochondria serve an important role in energy production and transfer to myocardial cells. More recently, mitochondria have been shown to play a key role in cell-death pathways by activating mitochondrial permeability transition pore formation and causing the release of several ...
Joel M, Weinberg, Pothana, Saikumar
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Over the past several decades, it has become widely recognized that the mitochondria serve an important role in energy production and transfer to myocardial cells. More recently, mitochondria have been shown to play a key role in cell-death pathways by activating mitochondrial permeability transition pore formation and causing the release of several ...
Joel M, Weinberg, Pothana, Saikumar
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Mitochondrial phospholipids: role in mitochondrial function
Journal of Bioenergetics and Biomembranes, 2015Mitochondria are essential components of eukaryotic cells and are involved in a diverse set of cellular processes that include ATP production, cellular signalling, apoptosis and cell growth. These organelles are thought to have originated from a symbiotic relationship between prokaryotic cells in an effort to provide a bioenergetic jump and thus, the ...
Edgard M, Mejia, Grant M, Hatch
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Mitochondrial functions of polymelanosomes
Comparative Biochemistry and Physiology, 1967Abstract 1. 1. Large cytoplasmic organelles containing melanin granules (polymelanosomes) were centrifugally isolated from the melanocytes of the Amphiuma tridactylum liver. 2. 2. These polymelanosomes have significant amounts of the following enzyme activities: succinic oxidase, cytochrome oxidase and monoamine oxidase. 3. 3.
M H, Van Woert +2 more
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Melatonin and mitochondrial function
Life Sciences, 2004Melatonin is a natural occurring compound with well-known antioxidant properties. In the last decade a new effect of melatonin on mitochondrial homeostasis has been discovered and, although the exact molecular mechanism for this effect remains unknown, it may explain, at least in part, the protective properties found for the indoleamine in degenerative
Josefa, Leon +5 more
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Mitochondrial function in shock
The American Journal of Emergency Medicine, 1984Studies utilizing animal models of circulatory shock have revealed mitochondrial structural and functional damage in the liver, kidney, and brain. Adenosine triphosphate (ATP) synthesis and calcium transport rates of these mitochondria decline significantly during circulatory shock.
L, Mela-Riker, H, Tavakoli
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Mitochondrial function in melanoma
Archives of Biochemistry and Biophysics, 2014Melanoma is the most lethal form of skin cancer and its incidence is rapidly rising. Breakthroughs in the understanding of the basic biology of melanoma in the past decade have yielded several new treatments, and advances continue to be made on a variety of fronts.
Nicholas, Theodosakis +3 more
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Mitochondrial Function in the Heart
Annual Review of Physiology, 1979The primary function of heart mitochondria is the production of A TP to support rhy thmic contraction and ion pumping reactions of the myocar dium. The heart can almost instantaneously modulate its rate of ATP production and oxygen consumption over at least a 5-fold range in response to diff erent work loads with only relatively minor changes in the ...
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Carnitine, mitochondrial function and therapy☆
Advanced Drug Delivery Reviews, 2009Carnitine is important for cell function and survival primarily because of its involvement in the multiple equilibria between acylcarnitine and acyl-CoA esters established through the enzymatic activities of the family of carnitine acyltransferases. These have different acyl chain-length specificities and intracellular compartment distributions, and ...
Zammit VA +3 more
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