Results 231 to 240 of about 1,044,161 (293)

Overview of methods that determine mitochondrial function in human disease. [PDF]

Metabolism
Sharma E, Fotooh Abadi L, Kombe Kombe JA, Kandala M, Parker J, Winicki N, Kelesidis T.   +6 more
europepmc   +1 more source

Functions of FKBP12 and Mitochondrial Cyclophilin Active Site Residues In Vitro and In Vivo inSaccharomyces cerevisiae [PDF]

, 1997
Kara Dolinski, Christian Schölz, R.Scott Muir, Sabine Rospert, Franz X. Schmid, María E. Cárdenas, Joseph Heitman   +6 more
openalex   +1 more source

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang, Yeoung Eun Choi, Song Yi Lee, Mrinmoy Karmakar, Qiaojun Hao, Junmin Lee, Hyun‐Jong Cho   +6 more
wiley   +1 more source

Alteration of cardiac energetics and mitochondrial function in doxorubicin‑induced cardiotoxicity: Molecular mechanism and prospective implications (Review). [PDF]

Int J Mol Med
Qing G, Huang C, Pei J, Peng B.
europepmc   +1 more source

Function of human mitochondrial 2,4-dienoyl-CoA reductase and rat monofunctional Δ3-Δ2-enoyl-CoA isomerase in β-oxidation of unsaturated fatty acids [PDF]

, 1999
Aner GURVITZ, Leila WABNEGGER, Ahmed I. YAGI, Maximilian BINDER, Andreas Hartig, Helmut RUIS, Barbara HAMILTON, Ian W. DAWES, J. Kalervo Hiltunen, Hanspeter ROTTENSTEINER   +9 more
openalex   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

GDF15 attenuates myocardial infarction-induced injury by preserving mitochondrial function and suppressing oxidative stress. [PDF]

Eur J Med Res
Yuan X, Wang C, Zhu H.
europepmc   +1 more source

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

IKZF1 exacerbates the inflammatory response by epigenetically modulating mitochondrial function following acute peritonitis. [PDF]

Front Immunol
Liu G, Hu P, Dong Y, Xu Y, Yang Z, Qi Z, Su Y.   +6 more
europepmc   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source