Results 51 to 60 of about 662,543 (166)

Data on mitochondrial function in skeletal muscle of old mice in response to different exercise intensity

Data in Brief, 2016
Endurance exercise is securely linked to muscle metabolic adaptations including enhanced mitochondrial function (“Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle” [1], “Effects of exercise on ...
Chounghun Kang, Wonchung Lim
doaj   +1 more source

Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA. [PDF]

PLoS ONE, 2008
Mitochondria form a highly dynamic tubular network, the morphology of which is regulated by frequent fission and fusion events. However, the role of mitochondrial fission in homeostasis of the organelle is still unknown.
Philippe A Parone, Sandrine Da Cruz, Daniel Tondera, Yves Mattenberger, Dominic I James, Pierre Maechler, François Barja, Jean-Claude Martinou   +7 more
doaj   +1 more source

Mitochondrial respiratory capacity in patients with acute episodes of bipolar disorder compared with clinical remission

European Psychiatry
Introduction Bipolar disorder (BD) is a chronic and recurrent disease characterized by acute mood episodes alternated with periods of euthymia. The available literature postulates that a biphasic dysregulation of mitochondrial bioenergetics might be ...
A. Giménez-Palomo, M. Guitart-Mampel, A. Meseguer, M. Valentí, L. Bracco, H. Andreu, E. Vieta, G. Garrabou, I. Pacchiarotti   +8 more
doaj   +1 more source

Local GHR roles in regulation of mitochondrial function through mitochondrial biogenesis during myoblast differentiation

Cell Communication and Signaling, 2023
Background Myoblast differentiation requires metabolic reprogramming driven by increased mitochondrial biogenesis and oxidative phosphorylation. The canonical GH-GHR-IGFs axis in liver exhibits a great complexity in response to somatic growth.
Bowen Hu, Changbin Zhao, Xiangchun Pan, Haohui Wei, Guodong Mo, Mingjian Xian, Wen Luo, Qinghua Nie, Hongmei Li, Xiquan Zhang   +9 more
doaj   +1 more source

Mitochondrial unfolded protein response gene CLPP changes mitochondrial dynamics and affects mitochondrial function [PDF]

PeerJ, 2019
Mitochondrial dynamics is associated with mitochondrial function, which is associated with diabetes. Although an important indicator of the mitochondrial unfolded protein response, to the best of our knowledge, CLPP and its effects on mitochondrial ...
GuiJun Wu, Qing Xiong, XiaoJun Wei, Ye Wang, XueMei Hu, GuangZhen He, LinJie Liu, QianHui Lai, Zhe Dai, Dhakal Anushesh, Yancheng Xu   +10 more
doaj   +2 more sources

Proteomic view of mitochondrial function [PDF]

Genome Biology, 2008
Genomic and proteomic studies have identified hundreds of proteins from mitochondria. A recent study has added a functional twist to these systematic approaches and identified novel mitochondrial modifiers and regulators.
Dimmer, Kai Stefan, Rapaport, Doron
openaire   +2 more sources

Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis

Heliyon
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving selective vulnerability of energy-intensive motor neurons (MNs). It has been unclear whether mitochondrial function is an upstream driver or a downstream modifier of ...
Calum Harvey, Marcel Weinreich, James A.K. Lee, Allan C. Shaw, Laura Ferraiuolo, Heather Mortiboys, Sai Zhang, Paul J. Hop, Ramona A.J. Zwamborn, Kristel van Eijk, Thomas H. Julian, Tobias Moll, Alfredo Iacoangeli, Ahmad Al Khleifat, John P. Quinn, Abigail L. Pfaff, Sulev Kõks, Joanna Poulton, Stephanie L. Battle, Dan E. Arking, Michael P. Snyder, Jan H. Veldink, Kevin P. Kenna, Pamela J. Shaw, Johnathan Cooper-Knock   +24 more
doaj   +1 more source

Feed Efficiency and Mitochondrial Function

Poultry Science, 2006
Studies have been conducted in our laboratory to assess differences in mitochondrial function and biochemistry in male broilers with high and low feed efficiency (FE) from the same genetic line and fed the same diet. Mitochondria obtained from broilers with low FE exhibited greater uncoupling of the electron transport chain (ETC) that was apparently ...
W, Bottje, N R, Pumford, C, Ojano-Dirain, M, Iqbal, K, Lassiter   +4 more
openaire   +2 more sources

Mitochondrial functionality in female reproduction

Postępy Higieny i Medycyny Doświadczalnej, 2017
In most animal species female germ cells are the source of mitochondrial genome for the whole body of individuals. As a source of mitochondrial DNA for future generations the mitochondria in the female germ line undergo dynamic quantitative and qualitative changes.
Łukasz, Gąsior, Regina, Daszkiewicz, Mateusz, Ogórek, Zbigniew, Polański   +3 more
openaire   +2 more sources

Computational Modeling of Mitochondrial Function [PDF]

, 2011
The advent of techniques with the ability to scan massive changes in cellular makeup (genomics, proteomics, etc.) has revealed the compelling need for analytical methods to interpret and make sense of those changes. Computational models built on sound physico-chemical mechanistic basis are unavoidable at the time of integrating, interpreting, and ...
Sonia, Cortassa, Miguel A, Aon
openaire   +2 more sources