Results 61 to 70 of about 13,400,035 (354)

Mitochondrial structure and function are disrupted by standard isolation methods. [PDF]

PLoS ONE, 2011
Mitochondria regulate critical components of cellular function via ATP production, reactive oxygen species production, Ca(2+) handling and apoptotic signaling.
Martin Picard, Tanja Taivassalo, Darmyn Ritchie, Kathryn J Wright, Melissa M Thomas, Caroline Romestaing, Russell T Hepple   +6 more
doaj   +1 more source

A mitochondrial import receptor for the ADP/ATP carrier [PDF]

, 1990
We have identified a mitochondrial outer membrane protein of 72 kd (MOM72) that exhibits the properties of an import receptor for the ADP/ATP carrier (AAC), the most abundant mitochondrial protein.
Arends, Attardi, Blake, Cheng, Cornwell, Fujiki, Fujiki, Griffiths, Griffiths, Hartl, Hartl, Hartl, Hawlitschek, Kleene, Klingenberg, Laemmli, Nicholson, Nicholson, Ohba, Ostermann, Pain, Pelham, Pfaller, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Rassow, Schleyer, Schleyer, Schleyer, Schwaiger, Smagula, Stuart, Stueber, Söllner, Söllner, Vestweber, Walter, Wickner, Young, Zimmermann, Zwizinski   +48 more
core   +1 more source

Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults

Physiological Reports, 2020
We investigated the acute and chronic effects of resistance training (RT) on skeletal muscle markers of mitochondrial content and remodeling in older, untrained adults.
Paulo H.C. Mesquita, Donald A. Lamb, Hailey A. Parry, Johnathon H. Moore, Morgan A. Smith, Christopher G. Vann, Shelby C. Osburn, Carlton D. Fox, Bradley A. Ruple, Kevin W. Huggins, Andrew D. Fruge, Kaelin C. Young, Andreas N. Kavazis, Michael D. Roberts   +13 more
doaj   +1 more source

Oxidative phosphorylation efficiency, proton conductance and reactive oxygen species production of liver mitochondria correlates with body mass in frogs [PDF]

, 2015
ody size is a central biological parameter affecting most biological processes (especially energetics) and mitochondria is a key organelle controlling metabolism and is also the cell's main source of chemical energy.
Dumet, A., Rey, B., Romestaing, C., Roussel, D., Salin, K., Voituron, Y.   +5 more
core   +3 more sources

Targeting Mitochondrial Function with Chemoptogenetics

Biomedicines, 2022
Mitochondria are ATP-generating organelles in eukaryotic cells that produce reactive oxygen species (ROS) during oxidative phosphorylation (OXPHOS). Mitochondrial DNA (mtDNA) is packaged within nucleoids and, due to its close proximity to ROS production,
Amy Romesberg, Bennett Van Houten
doaj   +1 more source

Hsp70 in mitochondrial biogenesis [PDF]

, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
A. Tzagoloff, A. Tzagoloff, A.J. Caplan, A.J. Caplan, B.D. Gambill, B.S. Glick, C.K. Suzuki, D. Ang, D. M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.P. Atencio, E. Ikeda, E. Kutejová, E.A. Craig, E.A. Craig, F.-U. Hartl, G.S.P. Groot, H.R.B. Pelham, J. Ostermann, J. Rassow, J.F. Dice, J.P. Hendrick, K. Liberek, L. Dyck van, M. Eilers, M. Kiebler, M. Schleyer, M.-J. Gething, M.Y. Cheng, N. Rowley, N. Wang, P. Borst, P. Terpstra, P.-J. Kang, R. A. Stuart, R.A. Stuart, R.A. Stuart, R.B. Deshaies, R.G. Hadikusumo, R.J. Nelson, R.P. Beckman, S. Lindquist, S. Rospert, S.T. Hwang, T. Langer, U.C. Manning-Krieg, W. Neupert, W. Neupert, W. Voos, W.J. Chirico, Z. Xia   +53 more
core   +1 more source

In silico simulation of reversible and irreversible swelling of mitochondria: The role of membrane rigidity [PDF]

, 2020
Mitochondria have been widely accepted as the main source of ATP in the cell. The inner mitochondrial membrane (IMM) is important for the maintenance of ATP production and other functions of mitochondria.
Arieli, Baranov, Bazil, Bazil, Beavis, Bernardi, Bernardi, Bernardi, Brenner, Carraro, Carroll, Chapa-Dubocq, Crockett, Giorgi, Griffiths, Halestrap, Halestrap, Halestrap, Halestrap, Hollander, Holmuhamedov, Hoppe, Ichas, Ichas, Igor Khmelinskii, Javadov, Javadov, Javadov, Kirichok, Kuznetsov, Kwong, Ladbrooke, Lehninger, Lopez-Crisosto, Makarov, Massari, O'Rourke, Palmer, Petronilli, Pokhilko, Sabzali Javadov, Scalettar, Selivanov, Shinitzky, Song, Szabo, Vladimir I. Makarov, Wodtke, Zaza Khuchua   +48 more
core   +1 more source

Natural Compounds Modulating Mitochondrial Functions [PDF]

Evidence-Based Complementary and Alternative Medicine, 2015
Mitochondria are organelles responsible for several crucial cell functions, including respiration, oxidative phosphorylation, and regulation of apoptosis; they are also the main intracellular source of reactive oxygen species (ROS). In the last years, a particular interest has been devoted to studying the effects on mitochondria of natural compounds of
GIBELLINI, Lara, BIANCHINI, ELENA, DE BIASI, SARA, NASI, Milena, COSSARIZZA, Andrea, PINTI, Marcello   +5 more
openaire   +3 more sources

hUC-MSC preserves erectile function by restoring mitochondrial mass of penile smooth muscle cells in a rat model of cavernous nerve injury via SIRT1/PGC-1a/TFAM signaling

Biological Research
Cavernous nerve injury-induced erectile dysfunction (CNI-ED) is a common complication following radical prostatectomy and severely affects patients’ quality of life. The mitochondrial impairment in corpus cavernosum smooth muscle cells (CCSMCs) may be an
Mengbo Yang, Xinda Chen, Ming Zhang, Xiaolin Zhang, Dongdong Xiao, Huiming Xu, Mujun Lu   +6 more
semanticscholar   +1 more source

Role of Cardiolipin in Mitochondrial Function and Dynamics in Health and Disease: Molecular and Pharmacological Aspects

Cells, 2019
In eukaryotic cells, mitochondria are involved in a large array of metabolic and bioenergetic processes that are vital for cell survival. Phospholipids are the main building blocks of mitochondrial membranes.
G. Paradies, Valeria Paradies, F. M. Ruggiero, G. Petrosillo   +3 more
semanticscholar   +1 more source