Results 181 to 190 of about 254,248 (207)

Does mitochondrial fusion require transmembrane potential?

Biochemistry (Moscow), 2015
Dissipation of transmembrane potential inhibits mitochondrial fusion and thus prevents reintegration of damaged mitochondria into the mitochondrial network. Consequently, damaged mitochondria are removed by autophagy. Does transmembrane potential directly regulate the mitochondrial fusion machinery?
I E, Karavaeva, K V, Shekhireva, F F, Severin, D A, Knorre   +3 more
openaire   +2 more sources

Regulation of mitochondrial fusion and division

Trends in Cell Biology, 2007
In many organisms, ranging from yeast to humans, mitochondria fuse and divide to change their morphology in response to a multitude of signals. During the past decade, work using yeast and mammalian cells has identified much of the machinery required for fusion and division, including the dynamin-related GTPases--mitofusins (Fzo1p in yeast) and OPA1 ...
Kara L, Cerveny, Yasushi, Tamura, Zhongyan, Zhang, Robert E, Jensen, Hiromi, Sesaki   +4 more
openaire   +2 more sources

Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

New England Journal of Medicine, 2013
Mitochondria fuse and divide in response to cell demands and environment. Alterations in mitochondrial dynamics underlie various human diseases, including cancer and neurologic and cardiovascular diseases. Defining the alterations may identify potential therapeutic targets.
openaire   +2 more sources

Rearrangements of mitochondrial DNA and the mitochondrial fusion-promoting plasmid (mF) are associated with defective mitochondrial fusion in Physarum polycephalum

Current Genetics, 1996
A specific linear mitochondrial plasmid (mF) is genetically associated with the fusion of mitochondria in the true slime mould, Physarum polycephalum. In matings between mF+ and mF- strains, which respectively carry and do not carry the mF plasmid, mitochondrial fusion occurs in the zygote.
H, Takano, K, Mori, S, Kawano, T, Kuroiwa   +3 more
openaire   +2 more sources

Mitochondrial Fusion and Heart Development

Science, 2013
Interrupting mitochondrial fusion inhibits cardiac differentiation by dysregulating a specific cell signaling pathway.
openaire   +2 more sources

Mitochondrial fission and fusion machineries

2004
Mitochondria are dynamic organelles, often fusing and dividing in response to changes in the cellular environment, during cell division and differentiation and under many other circumstances that affect mitochondrial function. Mitochondrial division is also an integral part of the apoptotic pathway in mammalian cells.
Lorena Griparic, Brian Head, Alexander M. van der Bliek   +2 more
openaire   +1 more source

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly  

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

Ca-A Cancer Journal for Clinicians, 2017
Cynthia Morata-Tarifa, Joyce M Slingerland   +1 more
exaly  

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

Ca-A Cancer Journal for Clinicians, 2020
Aaron J Grossberg, William L Hwang, Anirban Maitra   +2 more
exaly  

Oral complications of cancer and cancer therapy

Ca-A Cancer Journal for Clinicians, 2012
Joel B Epstein, Rene-Jean Bensadoun, Andrei Barasch   +2 more
exaly