Results 21 to 30 of about 540,064 (337)

Editing the Mitochondrial Genome

open access: yesNew England Journal of Medicine, 2020
Mending Mitochondrial Mutation For most patients with mitochondrial disorders, most of which are caused by mutations in genes in the mitochondrial genome, only symptomatic treatment is available.
Maria Falkenberg, Michio Hirano
openaire   +3 more sources

Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

open access: yesNature Communications, 2019
The role of mitochondrial DNA mutations in organismal fitness and lifespan have been studied in mitochondrial mutator models with varying results. Here, the authors generate a new APOBEC1 expression-based Drosophila mutator model and show that it has ...
Simonetta Andreazza   +15 more
doaj   +1 more source

The complete mitochondrial genome of Xenopsylla cheopis (Siphonaptera: Pulicidae)

open access: yesMitochondrial DNA. Part B. Resources, 2022
Xenopsylla cheopis, also called oriental rat flea, is an ectoparasite as well as disease vector for murine typhus and bubonic plague. In the study, the whole mitochondrial genome of X.
Furong Wei   +6 more
doaj   +1 more source

Ethics of modifying the mitochondrial genome [PDF]

open access: yes, 2010
Recent preclinical studies have shown the feasibility of specific variants of nuclear transfer to prevent mitochondrial DNA disorders. Nuclear transfer could be a valuable reproductive option for carriers of mitochondrial mutations.
Bredenoord, A L   +3 more
core   +2 more sources

Plant genetic reseources: effective utilization [PDF]

open access: yes, 2010
Characterizing better understanding the genome organization and differentiating identity of genotypes based on their morphology and genome characteristics are vital determinants in their commercialization, management of germplasm repositories, and ...
Budak, Hikmet
core   +1 more source

The complete mitochondrial genome of Caprella scaura (Crustacea, Amphipoda, Caprellidea), with emphasis on the unique gene order pattern and duplicated control region [PDF]

open access: yes, 2010
The nucleotide and amino acid sequences and the gene order of the mitochondrial genome are highly informative for studying phylogeny, population genetics, and phylogeography.
Aoki Masakazu N.   +4 more
core   +1 more source

Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3

open access: yesNature Communications, 2016
The post-transcriptional 5-methylcytosine (m5C) modification occurs in a wide range of nuclear-encoded RNAs. Here the authors identify the mitochondrial tRNA-Met as a target for the m5C methyltransferase NSun3—found mutated in a mitochondrial disease ...
Lindsey Van Haute   +18 more
doaj   +1 more source

The complete mitochondrial genome of Crematogaster matsumurai (Forel 1901) (Hymenoptera: Formicidae) and its phylogenetic relationship

open access: yesMitochondrial DNA. Part B. Resources, 2022
Crematogaster matsumurai (Forel 1901) is an important arboreal ant species commonly found on Phyllostachys heterocycla (Carr.) in Lishui, Zhejiang, China. This study analyzed the mitochondrial genome sequence of C.
Jin-chao Wang   +6 more
doaj   +1 more source

Characterization of the complete mitochondrial genome of Peniophora lycii (Russulales: Peniophoraceae) with its phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2021
Peniophora lycii is a resupinate lichen-like species distributed all over the world. In the present study, we sequenced and assembled the complete mitochondrial genome of Peniophora lycii. The size of the mitochondrial genome of P.
Qiufen Gou, Chaoqin Ren, Cong Peng
doaj   +1 more source

The highly rearranged mitochondrial genomes of the crabs Maja crispata and Maja squinado (Majidae) and gene order evolution in Brachyura [PDF]

open access: yes, 2017
We sequenced the mitochondrial genomes of the spider crabs Maja crispata and Maja squinado (Majidae, Brachyura). Both genomes contain the whole set of 37 genes characteristic of Bilaterian genomes, encoded on both \u3b1- and \u3b2-strands.
AD Miller   +67 more
core   +1 more source

Home - About - Disclaimer - Privacy