Results 21 to 30 of about 476,340 (314)
The complete mitochondrial genome of Xenopsylla cheopis (Siphonaptera: Pulicidae)
Xenopsylla cheopis, also called oriental rat flea, is an ectoparasite as well as disease vector for murine typhus and bubonic plague. In the study, the whole mitochondrial genome of X.
Furong Wei+6 more
doaj +1 more source
Ethics of modifying the mitochondrial genome [PDF]
Recent preclinical studies have shown the feasibility of specific variants of nuclear transfer to prevent mitochondrial DNA disorders. Nuclear transfer could be a valuable reproductive option for carriers of mitochondrial mutations.
Bredenoord, A L+3 more
core +2 more sources
Mitochondrial proteomics: analysis of a whole mitochondrial extract with two-dimensional electrophoresis [PDF]
Mitochondria are complex organelles, and their proteomics analysis requires a combination of techniques. The emphasis in this chapter is made first on mitochondria preparation from cultured mammalian cells, then on the separation of the mitochondrial proteins with two-dimensional electrophoresis (2DE), showing some adjustment over the classical ...
arxiv +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls+9 more
wiley +1 more source
The post-transcriptional 5-methylcytosine (m5C) modification occurs in a wide range of nuclear-encoded RNAs. Here the authors identify the mitochondrial tRNA-Met as a target for the m5C methyltransferase NSun3—found mutated in a mitochondrial disease ...
Lindsey Van Haute+18 more
doaj +1 more source
Cytochrome oxidase subunit VI of Trypanosoma brucei is imported without a cleaved presequence and is developmentally regulated at both RNA and protein levels [PDF]
Mitochondrial respiration in the African trypanosome undergoes dramatic developmental stage regulation. This requires co-ordinated control of components encoded by both the nuclear genome and the kinetoplast, the unusual mitochondrial genome of these ...
Benne R.+29 more
core +1 more source
Plant genetic reseources: effective utilization [PDF]
Characterizing better understanding the genome organization and differentiating identity of genotypes based on their morphology and genome characteristics are vital determinants in their commercialization, management of germplasm repositories, and ...
Budak, Hikmet
core +1 more source
Modeling Mito-nuclear Compatibility and its Role in Species Identification [PDF]
Mitochondrial genetic material is widely used for phylogenetic reconstruction and as a barcode for species identification. Here we study how mito-nuclear interactions affect the accuracy of species identification by mtDNA, as well as the speciation process itself.
arxiv +1 more source
A morphological view on mitochondrial protein targeting [PDF]
Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ades+55 more
core +1 more source
Cervus canadensis (Erxleben, 1777) has been used as a model species of Chronic Wasting Disease (CWD). We completed the mitochondrial genome of C. canadensis, susceptible to the CWD.
Hyo-Jin Kim+6 more
doaj +1 more source