Results 51 to 60 of about 1,901,465 (382)

Partial loss of MCU mitigates pathology in vivo across a diverse range of neurodegenerative disease models

open access: yesCell Reports
Summary: Mitochondrial calcium (Ca2+) uptake augments metabolic processes and buffers cytosolic Ca2+ levels; however, excessive mitochondrial Ca2+ can cause cell death.
Madeleine J. Twyning   +9 more
doaj   +1 more source

Mitochondria-encoded genes contribute to evolution of heat and cold tolerance in yeast [PDF]

open access: yes, 2019
Genetic analysis of phenotypic differences between species is typically limited to interfertile species. Here, we conducted a genome-wide noncomplementation screen to identify genes that contribute to a major difference in thermal growth profile between ...
Fay, Justin C   +4 more
core   +2 more sources

MitoFish and MiFish Pipeline: A Mitochondrial Genome Database of Fish with an Analysis Pipeline for Environmental DNA Metabarcoding

open access: yesMolecular biology and evolution, 2018
Fish mitochondrial genome (mitogenome) data form a fundamental basis for revealing vertebrate evolution and hydrosphere ecology. Here, we report recent functional updates of MitoFish, which is a database of fish mitogenomes with a precise annotation ...
Yukuto Sato   +4 more
semanticscholar   +1 more source

Transformation of the mitochondrial genome

open access: yesThe International Journal of Developmental Biology, 2013
Although mitochondrial transformation is highly desirable in mammals and plants, it is only possible in two unicellular organisms, the budding yeast Saccharomyces cerevisiae and the unicellular green alga Chlamydomonas reinhardtii. Here, we give an overview of the attempts made to transform mitochondria of mammals and plants and the possible reasons ...
Véronique Larosa, Claire Remacle
openaire   +4 more sources

Origin of minicircular mitochondrial genomes in red algae

open access: yesNature Communications, 2023
Eukaryotic organelle genomes are generally of conserved size and gene content within phylogenetic groups. However, significant variation in genome structure may occur.
Yongsung Lee   +9 more
doaj   +1 more source

The complete mitochondrial genome of the early flowering plant Nymphaea colorata is highly repetitive with low recombination

open access: yesBMC Genomics, 2018
BackgroundMitochondrial genomes of flowering plants (angiosperms) are highly dynamic in genome structure. The mitogenome of the earliest angiosperm Amborella is remarkable in carrying rampant foreign DNAs, in contrast to Liriodendron, the other only ...
S. Dong   +7 more
semanticscholar   +1 more source

The complete mitochondrial genome of Caprella scaura (Crustacea, Amphipoda, Caprellidea), with emphasis on the unique gene order pattern and duplicated control region [PDF]

open access: yes, 2010
The nucleotide and amino acid sequences and the gene order of the mitochondrial genome are highly informative for studying phylogeny, population genetics, and phylogeography.
Aoki Masakazu N.   +4 more
core   +1 more source

High and Variable Rates of Repeat-Mediated Mitochondrial Genome Rearrangement in a Genus of Plants

open access: yesMolecular biology and evolution, 2018
For 30 years, it has been clear that angiosperm mitochondrial genomes evolve rapidly in sequence arrangement (i.e., synteny), yet absolute rates of rearrangement have not been measured in any plant group, nor is it known how much these rates vary.
L. W. Cole   +3 more
semanticscholar   +1 more source

Screening for the ancient polar bear mitochondrial genome reveals low integration of mitochondrial pseudogenes (numts) in bears

open access: yesMitochondrial DNA. Part B. Resources, 2017
Phylogenetic analyses of nuclear and mitochondrial genomes indicate that polar bears captured the brown bear mitochondrial genome 160,000 years ago, leading to an extinction of the original polar bear mitochondrial genome.
Fritjof Lammers   +4 more
doaj   +1 more source

The developmental cell biology of Trypanosoma brucei [PDF]

open access: yes, 2005
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R
core   +1 more source

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