Results 51 to 60 of about 1,628,733 (342)

The mitochondrial genome of Endoconidiophora resinifera is intron rich

Scientific Reports, 2018
Endoconidiophora resinifera (=Ceratocystis resinifera) is a blue-stain fungus that occurs on conifers. The data showed that the Endoconidiophora resinifera mitochondrial genome is one of the largest mitochondrial genomes (>220 kb) so far reported among ...
A. Zubaer, Alvan Wai, G. Hausner
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

The Mitochondrial Genome of Toxocara canis

PLoS Neglected Tropical Diseases, 2008
Toxocara canis (Ascaridida: Nematoda), which parasitizes (at the adult stage) the small intestine of canids, can be transmitted to a range of other mammals, including humans, and can cause the disease toxocariasis. Despite its significance as a pathogen, the genetics, epidemiology and biology of this parasite remain poorly understood.
Jex, AR, Waeschenbach, A, Littlewood, DTJ, Hu, M, Gasser, RB   +4 more
openaire   +7 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Early-stage idiopathic Parkinson’s disease is associated with reduced circular RNA expression

npj Parkinson's Disease
Neurodegeneration in Parkinson’s disease (PD) precedes diagnosis by years. Early neurodegeneration may be reflected in RNA levels and measurable as a biomarker. Here, we present the largest quantification of whole blood linear and circular RNAs (circRNA)
Benjamin J. Whittle, Osagie G. Izuogu, Hannah Lowes, Dasha Deen, Angela Pyle, Jon Coxhead, Rachael A. Lawson, Alison J. Yarnall, Michael S. Jackson, Mauro Santibanez-Koref, Gavin Hudson   +10 more
doaj   +1 more source

Complete mitochondrial genome of Angelica dahurica and its implications on evolutionary analysis of complex mitochondrial genome architecture in Apiaceae

Frontiers in Plant Science
Angelica dahurica is a kind of Chinese traditional herbs with economic and ornament value, widely distributed in China. Despite its significance, there have been limited comprehensive investigations on the genome of A.
Yuan-Yuan Li, You-Yan Liu, Xu Zeng, Ping Wu, Qing-Miao Li, Shun-Xing Guo, Zhi-Gang Hao, Zhi-Gang Hao, Zhi-Gang Hao, Zhi-Gang Hao   +9 more
doaj   +1 more source

Complete mitochondrial genome sequence of Afla-Guard®, commercially available non-toxigenic Aspergillus flavus

Mitochondrial DNA. Part B. Resources, 2020
Afla-Guard® is a commercial non-toxigenic Aspergillus flavus strain used to decrease aflatoxin contamination level in field. Its mitochondrial genome was sequenced, showing that its length is 29,208 bp with typical configuration of Aspergillus ...
Jongsun Park, Mi-Kyung Lee, Jae-Hyuk Yu, Jong-Hwa Kim, Kap-Hoon Han   +4 more
doaj   +1 more source

PacBio-Based Mitochondrial Genome Assembly of Leucaena trichandra (Leguminosae) and an Intrageneric Assessment of Mitochondrial RNA Editing

Genome Biology and Evolution, 2018
Reconstructions of vascular plant mitochondrial genomes (mt-genomes) are notoriously complicated by rampant recombination that has resulted in comparatively few plant mt-genomes being available. The dearth of plant mitochondrial resources has limited our
L. Kovar, M. Nageswara-Rao, Sealtiel Ortega-Rodriguez, Diana V. Dugas, S. Straub, R. Cronn, S. Strickler, C. Hughes, K. Hanley, Deyra N. Rodriguez, B. Langhorst, E. Dimalanta, C. Bailey   +12 more
semanticscholar   +1 more source

The Mitochondrial Genome of Baylisascaris procyonis

PLoS ONE, 2011
Baylisascaris procyonis (Nematoda: Ascaridida), an intestinal nematode of raccoons, is emerging as an important helminthic zoonosis due to serious or fatal larval migrans in animals and humans. Despite its significant veterinary and public health impact, the epidemiology, molecular ecology and population genetics of this parasite remain largely ...
Jiabo Deng, Yue Xie, Xiaobin Gu, Guangyou Yang, Ning Yan, Deying Yang, Jingchao Lan, Guiying Hao, Zhihe Zhang, Huaming Nie, Xuerong Peng, Yan Fu, Lili Niu, Chengdong Wang, Shuxian Wang, Qiang Wang   +15 more
openaire   +5 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source