Results 71 to 80 of about 328,957 (317)

Mitochondrial genome Amphiprion frenatus

, 2018
The mitochondrial genome of Amphiprion frenatus, in fasta format. The mitochondrial genome was obtained by assembling short Illumina reads with MITObim.
Litsios, Glenn, Marcionetti, Anna, Anna Marcionetti (5016116), Salamin, Nicolas, Nicolas Salamin (2923683), Victor Rossier (5016113), Rossier, Victor, Joris Bertrand (5016152), Glenn Litsios (3248730), Bertrand, Joris   +9 more
core   +1 more source

Experiences from dual genome next-generation sequencing panel testing for mitochondrial disorders: a comprehensive molecular diagnosis

Frontiers in Genetics
IntroductionThe molecular diagnosis of mitochondrial disorders is complicated by phenotypic variability, genetic heterogeneity, and the complexity of mitochondrial heteroplasmy.
Elizabeth Gorman, Hongzheng Dai, Hongzheng Dai, Yanming Feng, William James Craigen, William James Craigen, David C. Y. Chen, Fan Xia, Fan Xia, Linyan Meng, Linyan Meng, Pengfei Liu, Pengfei Liu, Robert Rigobello, Arpita Neogi, Christine M. Eng, Christine M. Eng, Yue Wang, Yue Wang   +18 more
doaj   +1 more source

Characterization and phylogenetic analysis of the complete mitochondrial genome of Clavulina sp. (Cantharellales: Clavulinaceae)

Mitochondrial DNA. Part B. Resources, 2020
In this study, the complete mitochondrial genome of Clavulina sp. was sequenced and assembled. The complete mitochondrial genome of Clavulina sp. contains 20 protein-coding (PCG) genes, 2 ribosomal RNA (rRNA) genes, and 25 transfer RNA (tRNA) genes.
Maoling Tan, Gang Zhao
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Orussus abietinus mitochondrial genome assembly

, 2018
The Baylor College of Medicine has sequenced and annotated the Orussus abietinus genome as part of the i5k pilot project. This dataset represents a targeted assembly and annotation of the mitochondrial genome.
Jan Philip Oeyen (17479215)
core   +1 more source

Mitochondrial genome alignment

, 2023
Mitochondrial Genome alignment, representing each of the families of anisoptera for which there is a mitochondrial genomes.
Ethan Tolman (14002962), Jessica L. Ware (9024464)   +1 more
core   +1 more source

The mitochondrial brain: From mitochondrial genome to neurodegeneration

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2010
Mitochondrial DNA mutations are an important cause of neurological disease. The clinical presentation is very varied in terms of age of onset and different neurological signs and symptoms. The clinical course varies considerably but in many patients there is a progressive decline, and in some evidence of marked neurodegeneration.
Turnbull, H, Lax, N, Diodato, D, Ansorge, O, Turnbull, D   +4 more
openaire   +3 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Mitochondrial genome annotation Amphiprion frenatus

, 2018
Mitochondrial genome annotation for Amphiprion frenatus, in csv format. MitoAnnotator and MitoFish were used to obtain the mitochondrial genome annotation.
Litsios, Glenn, Marcionetti, Anna, Anna Marcionetti (5016116), Salamin, Nicolas, Nicolas Salamin (2923683), Victor Rossier (5016113), Rossier, Victor, Joris Bertrand (5016152), Glenn Litsios (3248730), Bertrand, Joris   +9 more
core   +1 more source

p53 as guardian of the mitochondrial genome [PDF]

FEBS Letters, 2016
Participating in the repair of nuclear DNA is one mechanism by which p53 suppresses tumorigenesis, but there is growing evidence that p53 also helps maintain the mitochondrial genome through its translocation into mitochondria and interactions with mtDNA repair proteins. Because of the susceptibility of mtDNA to oxidative damage and replication errors,
Ji-Hoon, Park, Jie, Zhuang, Jie, Li, Paul M, Hwang   +3 more
openaire   +2 more sources