Results 71 to 80 of about 540,064 (337)

Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans [PDF]

open access: yes, 2018
Background: Advances in automated image-based microscopy platforms coupled with high-throughput liquid workflows have facilitated the design of large-scale screens utilising multicellular model organisms such as Caenorhabditis elegans to identify genetic
Artal Sanz, Marta   +10 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Characterization and phylogenetic analysis of the complete mitochondrial genome of Clavulina sp. (Cantharellales: Clavulinaceae)

open access: yesMitochondrial DNA. Part B. Resources, 2020
In this study, the complete mitochondrial genome of Clavulina sp. was sequenced and assembled. The complete mitochondrial genome of Clavulina sp. contains 20 protein-coding (PCG) genes, 2 ribosomal RNA (rRNA) genes, and 25 transfer RNA (tRNA) genes.
Maoling Tan, Gang Zhao
doaj   +1 more source

Characterization of the complete mitochondrial genome of the Lesser Spotted Woodpecker (Dryobates minor) and its phylogenetic position

open access: yesMitochondrial DNA. Part B. Resources, 2022
In this study, we sequenced and assembled the complete mitochondrial genome of Dryobates minor by next-generation sequencing. The mitochondrial genome of Dryobates minor is 16,847 bp in length and consists of 13 protein-coding genes (PCGS), two ribosomal
Junda Chen   +6 more
doaj   +1 more source

Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA [PDF]

open access: bronze, 2022
Romain Guitton   +5 more
openalex   +1 more source

Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]

open access: yes, 2014
Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa   +6 more
core   +1 more source

Multilevel selection on mitochondrial genomes

open access: yesCurrent Opinion in Genetics & Development, 2023
Mitochondria are vital organelles for life in eukaryotes, taking centre stage in the process of cellular respiration. This process is regulated via a series of finely coordinated obligate interactions of molecules encoded by two genomes: nuclear DNA and mitochondrial DNA.
Camus, MF, Dhawanjewar, AS
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The first complete mitochondrial genome assembly and comparative analysis of the fern Blechnaceae family: Blechnopsis orientalis

open access: yesFrontiers in Plant Science
IntroductionBlechnopsis orientalis (L.) C. Presl is a medicinal and edible fern species belonging to the Blechnaceae family. Currently, the complete mitochondrial genome of B. orientalis, as well as those of other Blechnaceae species, remains unreported,
Yutong Huang   +9 more
doaj   +1 more source

A fragmented metazoan organellar genome [PDF]

open access: yes, 2008
Background: Animal mitochondrial (mt) genomes are characteristically circular molecules of ~16–20 kb. Medusozoa (Cnidaria excluding Anthozoa) are exceptional in that their mt genomes are linear and sometimes subdivided into two to presumably four ...
Erpenbeck, Dirk   +2 more
core   +1 more source

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