Results 91 to 100 of about 498,645 (208)

Living unicellular eukaryote Tetrahymena pyriformis as a model for study of mitochondrial energetics in mammalian cells under conditions of reduced oxidative metabolism.

, 2010
Some “animal-like” protozoa are used instead of mammalian cells in diverse investigations. _Tetrahymena pyriformis_ cells in stationary phase of growth and washed from oxidative substrates (_T.pyriformis_) function under conditions of ...
Elena Mokhova
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Structural and functional studies of mitochondrial NADH:ubiquinone oxidoreductase (complex I)

, 2010
NADH:ubiquinone oxidoreductase (complex I) is the largest and most complicated enzyme in the mitochondrial electron transfer chain. It catalyses the oxidation of NADH and the reduction of ubiquinone, coupled to the translocation of protons across the ...

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Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration [PDF]

, 2013
Transcription factor Nrf2 and its repressor Keap1 regulate a network of cytoprotective genes involving more than 1% of the genome, their best known targets being drug-metabolizing and antioxidant genes.
Iain Hargreaves, Land, John M., Kira M. Holmström, Andrey Y. Abramov, Chalasani, A, Annapurna Chalasani, Holmstrom, KM, Masayuki Yamamoto, Baird, Liam, Baird, L, John M. Land, Yamamoto, Masayuki, Lee Stanyer, Land, JM, Dinkova-Kostova, AT, Holmström, Kira M., Liam Baird, Albena T. Dinkova-Kostova, Ying Zhang, Abramov, Andrey Y., Zhang, Y, Hargreaves, Iain, Chalasani, Annapurna, Abramov, AY, Stanyer, L, Hargreaves, IP, Yamamoto, M, Zhang, Ying, Stanyer, Lee, Dinkova-Kostova, Albena T.; id_orcid   +29 more
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Mitochondrial membrane potential probes and the proton gradient: a practical usage guide

BioTechniques, 2011
Fluorescent probes for monitoring mitochondrial membrane potential are frequently used for assessing mitochondrial function, particularly in the context of cell fate determination in biological and biomedical research.
Seth W. Perry, John P. Norman, Justin Barbieri, Edward B. Brown, Harris A. Gelbard   +4 more
doaj   +1 more source

Translocation arrest by reversible folding of a precursor protein imported into mitochondria [PDF]

, 1989
Passage of precursor proteins through translocation contact sites of mitochondria was investigated by studying the import of a fusion protein consisting of the NH2-terminal 167 amino acids of yeast cytochrome b2 precursor and the complete mouse ...
Herzog, Volker, Hartl, Franz-Ulrich, Rassow, Joachim, Neupert, Walter, Guiard, Bernard, Wienhues, Ulla   +5 more
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Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

PLoS ONE, 2009
PTEN-induced novel kinase 1 (PINK1) mutations are associated with autosomal recessive parkinsonism. Previous studies have shown that PINK1 influences both mitochondrial function and morphology although it is not clearly established which of these are ...
Anna Sandebring, Kelly Jean Thomas, Alexandra Beilina, Marcel van der Brug, Megan M Cleland, Rili Ahmad, David W Miller, Ibardo Zambrano, Richard F Cowburn, Homira Behbahani, Angel Cedazo-Mínguez, Mark R Cookson   +11 more
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The Effects of Microseconds Electroporation on Pore Size, Viability and Mitochondrial Membrane Potential of Cervical Cancer Cells [PDF]

Objective: Electroporation (EP) is a method in which the membrane permeability is increased by applying electrical pulses. The determination of modifications that occur in cells subsequent to EP with varying pulse parameters holds significant importance ...
Güney GÜRSOY, Meriç Arda ESMEKAYA, Zehra ÇİÇEK   +2 more
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Rab11b is necessary for mitochondrial integrity and function in gut epithelial cells

Frontiers in Cell and Developmental Biology
IntroductionThe RAB11 family of small GTPases are intracellular regulators of membrane and vesicular trafficking. We recently reported that RAB11A and RAB11B redundantly regulate spindle dynamics in dividing gut epithelial cells.
Ivor Joseph, Jiangmeng Han, Jared Bianchi-Smak, Jiaxing Yang, Jagannatham Naidu Bhupana, Jagannatham Naidu Bhupana, Juan Flores, Jack Delucia, Tracy S. Tran, James R. Goldenring, Edward M. Bonder, Nan Gao, Nan Gao   +12 more
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Imaging flow cytometry reveals divergent mitochondrial phenotypes in mitochondrial disease patients

iScience
Summary: Traditional classification by clinical phenotype or oxidative phosphorylation (OXPHOS) complex deficiencies often fails to clarify complex genotype-phenotype correlations in mitochondrial disease.
Irena.J.J. Muffels, Richard Rodenburg, Hanneke L.D. Willemen, Désirée van Haaften-Visser, Hans Waterham, Niels Eijkelkamp, Sabine A. Fuchs, Peter M. van Hasselt   +7 more
doaj   +1 more source

Nonequivalence of membrane voltage and ion-gradient as driving forces for the bacterial flagellar motor at low load

, 2007
Many bacterial species swim using. agella. The. flagellar motor couples ion. ow across the cytoplasmic membrane to rotation. Ion flow is driven by both a membrane potential (Vm) and a transmembrane concentration gradient. To investigate their relation to
Richard M. Berry, Berry, RM, Teuta Pilizota, Leake, Mark C., Pilizota, T, Berry, Richard, Chien-jung Lo, Leake, MC, Lo, Chien-Jung, Pilizota, Teuta, Mark C. Leake, Berry, Richard M., Lo, CJ, Leake, Mark   +13 more
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