Results 71 to 80 of about 498,645 (208)

Hsp70 in mitochondrial biogenesis [PDF]

, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
Stuart, Rosemary A., Neupert, Walter, Cyr, Douglas M.   +2 more
core   +1 more source

A comparative study of cryodamages of boar spermatozoa frozen with conventional liquid nitrogen vapour freezing method

Indian Journal of Animal Sciences, 2014
The objective of the present study was to quantify the various cryodamages that boar spermatozoa undergo following freezing with conventional liquid nitrogen vapour freezing method.
S K BAISHYA, R K BISWAS, G KADIRVEL, B C DEKA, SURESH KUMAR, D R THAKURIA   +5 more
doaj   +1 more source

Caspase-3 Activation Correlates With the Initial Mitochondrial Membrane Depolarization in Neonatal Cerebellar Granule Neurons

Frontiers in Cell and Developmental Biology, 2020
In this study we evaluated the effect of the reduction in the endoplasmic reticulum calcium concentration ([Ca2+]ER), changes in the cytoplasmic calcium concentration ([Ca2+]i), alteration of the mitochondrial membrane potential, and the ER stress in the
Edaena Benítez-Rangel, Edaena Benítez-Rangel, Mauricio Olguín-Albuerne, María Cristina López-Méndez, Guadalupe Domínguez-Macouzet, Agustín Guerrero-Hernández, Julio Morán   +6 more
doaj   +1 more source

Import pathways of precursor proteins into mitochondria [PDF]

, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Pfaller, Rupert, Pfanner, Nikolaus, Steger, Heinrich F., Rassow, Joachim, Neupert, Walter   +4 more
core  

Deceleration of fusion–fission cycles improves mitochondrial quality control during aging

, 2012
Mitochondrial dynamics and mitophagy play a key role in ensuring mitochondrial quality control. Impairment thereof was proposed to be causative to neurodegenerative diseases, diabetes, and cancer.
Michael Meyer-Hermann, Michael Meyer-Hermann (124166), Andreas S. Reichert (124162), Reichert Andreas S., Heinz D. Osiewacz (120841), Figge, Marc Thilo, Reichert, Andreas S, Marc Thilo Figge, Heinz D Osiewacz, Reichert, Andreas, Meyer-Hermann Michael, Meyer-Hermann, Michael (Prof. Dr.), Osiewacz Heinz D., Meyer-Hermann, Michael, Osiewacz, Heinz D., Andreas S Reichert, Figge Marc Thilo, Marc Thilo Figge (155511), Osiewacz, Heinz D   +18 more
core   +1 more source

Protein folding causes an arrest of preprotein translocation into mitochondria in vivo [PDF]

, 1991
With vital yeast cells, a hybrid protein consisting of the amino- terminal third of the precursor to cytochrome b2 and of the entire dihydrofolate reductase was arrested on the import pathway into mitochondria.
W Neupert, M Schleyer, Pfanner, Nikolaus, Schleyer, Manfred, Neupert, Walter, Horwich, Arthur, B Guiard, Guiard, Bernard, N Pfanner, Wienhues, Ulla, K Becker, A L Horwich, Tropschug, Maximilian, Becker, Karin, U Wienhues, M Tropschug   +15 more
core   +1 more source

Autophagy compensates for defects in mitochondrial dynamics.

PLoS Genetics, 2020
Compromising mitochondrial fusion or fission disrupts cellular homeostasis; however, the underlying mechanism(s) are not fully understood. The loss of C.
Simon Haeussler, Fabian Köhler, Michael Witting, Madeleine F Premm, Stéphane G Rolland, Christian Fischer, Laetitia Chauve, Olivia Casanueva, Barbara Conradt   +8 more
doaj   +1 more source

Simultaneous imaging of cell and mitochondrial membrane potentials

Biophysical Journal, 1989
The distribution of charged membrane-permeable molecular probes between intracellular organelles, the cytoplasm, and the outside medium is governed by the relative membrane electrical potentials of these regions through coupled equilibria described by the Nernst equation. A series of highly fluorescent cationic dyes of low membrane binding and toxicity
Farkas, D.L., Wei, M.D., Febbroriello, P., Carson, J.H., Loew, L.M.   +4 more
openaire   +2 more sources

Protein-induced modulation of chloroplast membrane morphology

, 2012
Organelles are surrounded by membranes with a distinct lipid and protein composition. While it is well established that lipids affect protein functioning and vice versa, it has been only recently suggested that elevated membrane protein concentrations ...
Maik S Sommer, Enrico eSchleiff, Machettira, Anu Bheemaiah, Anu B. Machettira, Englich, Gisela, Anu B Machettira, Benjamin LM Weis, Lucia E. Groß, Giesela eEnglich, Enrico Schleiff, Weis, Benjamin L., Gisela Englich, Lucia E Groß, Schleiff, Enrico, Königer, Martina, Martina eKöniger, Bodo Tillmann, Groß, Lucia E., Sommer, Maik Sascha, Benjamin L. Weis, Bodo eTillmann, Martina Königer, Tillmann, Bodo, Maik S. Sommer   +23 more
core   +1 more source

A mitochondrially targeted compound delays aging in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox biology

Redox Biology, 2014
A recent study revealed a mechanism of delaying aging in yeast by a natural compound which specifically impacts mitochondrial redox processes. In this mechanism, exogenously added lithocholic bile acid enters yeast cells, accumulates mainly in the inner ...
Michelle T. Burstein, Vladimir I. Titorenko   +1 more
doaj   +1 more source