Results 81 to 90 of about 498,645 (208)

PHENOTYPIC AND METABOLIC FEATURES OF CD4 AND CD8 T CELLS OF AN ELITE CONTROLLER

Problems of Infectious and Parasitic Diseases
Background: People living with HIV (PLHIV) who are capable of long-term viral suppression in the absence of antiretroviral therapy (ART) are defined as elite controllers (EC).
Damian Vangelov, Radoslava Emilova, Yana Todorova, Svetla Blazheva, Ivailo Alexiev, Tsetsa Doichinova, Maria Nikolova   +6 more
doaj   +1 more source

Effects of disialoganglioside GD3 on the mitochondrial membrane potential

FEBS Letters, 2005
GD3 is an intracellular mediator of apoptotic signaling. Although GD3 is known to directly act on mitochondria, the dynamic responses of individual mitochondria to GD3 remain to be elucidated. In the current study, the membrane potential of single mitochondria is observed in the presence of GD3 or its analogues.
Higuchi, Yu, Miura, Tsuyoshi, Kajimoto, Tetsuya, Ohta, Yoshihiro   +3 more
openaire   +2 more sources

hUCMSC mitochondrial EVs confer neuroprotection after ischemia by Tom1l2-mediated mitochondrial fusion and Crls1–cardiolipin axis reprogramming

Redox Biology
Mitochondrial dysfunction is a central driver of irreversible neuronal injury following ischemic stroke (IS); yet effective strategies to restore mitochondrial function and promote long-term neurological recovery remain limited.
Ziheng Li, Xingjia Zhu, Weiquan Liao, Rui Jiang, Enze Sang, Jue Zhu, Gaojia Sun, Zhichao Lu, Chenxing Wang, Yi Jiang, Jian Chen, Peipei Gong, Qianqian Liu   +12 more
doaj   +1 more source

Electrical homeostasis of the inner mitochondrial membrane potential

Physical Biology
Abstract The electric potential across the inner mitochondrial membrane must be maintained within certain bounds for the proper functioning of the cell. A feedback control mechanism for the homeostasis of this membrane potential is proposed whereby an increase in the electric field decreases the rate-limiting steps of the electron ...
Peyman Fahimi, Lázaro A M Castanedo, P Thomas Vernier, Chérif F Matta   +3 more
openaire   +3 more sources

Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells

, 2010
Background: Mitochondria, the main suppliers of cellular energy, are dynamic organelles that fuse and divide frequently. Constraining these processes impairs mitochondrial is closely linked to certain neurodegenerative diseases.
Strecker, V., Busch, K., Winfried Haase, Wittig, I., Bereiter-Hahn, Jürgen, Haase, W., Karin Busch, Joos, Friederike, Ilka Wittig, Britta Muster, Jürgen Bereiter-Hahn, Wittig, Ilka, Wladislaw Kohl, Valentina Strecker, Busch, Karin, Haase, Winfried, Joos, F., Muster, Britta, Kohl, W., Strecker, Valentina, Friederike Joos, Muster, B., Bereiter-Hahn, J., Kohl, Wladislaw   +23 more
core   +1 more source

Metabolic consequences of neuronal mitochondrial fission ablation [PDF]

, 2016
Dynamin-related protein 1 (Drp1), the main mammalian mediator of mitochondrial fission, has an especially important role in neuronal development, such that its deletion gives rise to pre- or perinatal lethality.
Restelli, Lisa Michelle
core   +1 more source

Evaluation of mitochondrial membrane potential.

, 2023
The panel of flow cytometry was stained with JC-1 for fresh control (A), frozen control (B), frozen trehalose (C), and frozen gentiobiose (D). The top right quadrant represents the percentage of values showing the proportion of sperm with high ...
Gholamhossein Riazi (7349048), Loghman Alaei (15286049), Vahid Esmaeili (12700352), Touba Nadri (15286046), Mohsen Sharafi (7349057), Abdolhossein Shahverdi (2388424), Dariush Gholami (7349042)   +6 more
core   +1 more source

Imaging Reversible Mitochondrial Membrane Potential Dynamics with a Small Molecule, Permeable, Internally Redistributing for Inner Membrane Targeting Rhodamine Voltage Reporter

, 2020
Mitochondria are the site of aerobic respiration, producing ATP via oxidative phosphorylation as protons flow down their electrochemical gradient through ATP synthase.
Pavel, Klier, Evan, Miller, Julia, Martin   +2 more
core   +1 more source

Mechanisms of hepatocellular toxicity associated with dronedarone and other mitochondrial toxicants [PDF]

, 2014
Idiosyncratic drug-induced liver injury is a rare toxic event that typically occurs at therapeutic doses, which are generally safe to the majority of patients.
Felser, Andrea Debora
core   +1 more source

Arabidopsis thaliana Embryo Sac Mitochondrial Membrane Potential Stain

Bio-Protocol, 2014
The aim of this experiment is to study mitochondrial functional status in Arabidopsis embryo sacs using the membrane potential indicator JC-1. Changes in the membrane potential are presumed to be due to the opening of the mitochondrial permeability ...
María Martin, Diego Fiol, Eduardo Zabaleta, Gabriela Pagnussat   +3 more
doaj   +1 more source