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Assembling the mitochondrial outer membrane

Nature Structural & Molecular Biology, 2004
The general preprotein translocase of the outer mitochondrial membrane (TOM complex) transports virtually all mitochondrial precursor proteins, but cannot assemble outer-membrane precursors into functional complexes. A recently discovered sorting and assembly machinery (SAM complex) is essential for integration and assembly of outer-membrane proteins ...
Pfanner, Nikolaus   +3 more
openaire   +3 more sources

Biogenesis of mitochondrial membrane proteins

Current Opinion in Cell Biology, 2009
Mitochondria are ubiquitous, double-membrane bound organelles, which have developed from endosymbiotic alpha-proteobacteria during evolution. Outer and inner membranes of mitochondria are equipped with characteristic sets of membrane proteins required for energy conversion, metabolite and protein transport, membrane fusion and fission, and signal ...
Becker, Thomas   +3 more
openaire   +3 more sources

Oxygen Diffusion Through Mitochondrial Membranes

1989
The effect of the mitochondrial membrane on the oxygen supply to the interior of mitochondria was analyzed with a cylinder model of diffusion. This estimation is based on the assumption that cytochrome a,a3 is distributed only on the inner surface of the mitochondrial inner membrane.
T, Koyama, M, Kinjo, T, Araiso
openaire   +2 more sources

Mitochondrial Fusion Through Membrane Automata

2014
Studies have shown that malfunctions in mitochondrial processes can be blamed for diseases. However, the mechanism behind these operations is yet not sufficiently clear. In this work we present a novel approach to describe a biomolecular model for mitochondrial fusion using notions from the membrane computing.
Konstantinos, Giannakis   +1 more
openaire   +2 more sources

Lipid metabolism in mitochondrial membranes

Journal of Inherited Metabolic Disease, 2014
AbstractMitochondrial membranes have a unique lipid composition necessary for proper shape and function of the organelle. Mitochondrial lipid metabolism involves biosynthesis of the phospholipids phosphatidylethanolamine, cardiolipin and phosphatidylglycerol, the latter is a precursor of the late endosomal lipid bis(monoacylglycero)phosphate.
openaire   +2 more sources

Incorporation of β-sitosterol into mitochondrial membrane enhances mitochondrial function by promoting inner mitochondrial membrane fluidity

Journal of Bioenergetics and Biomembranes, 2012
Recent findings suggest that mitochondrial membrane fluidity could influence mitochondrial energy metabolism. β-sitosterol (BS) is a common plant sterol that is prevalent in plant oils, nuts, cereals and plant food products. Its chemical structure is very similar to that of cholesterol.
Chun, Shi, Fengming, Wu, Jie, Xu
openaire   +2 more sources

High-conductance pathways in mitochondrial membranes

Journal of Bioenergetics and Biomembranes, 1992
The outer and inner membranes of mitochondria have recently been studied with the patch clamp technique. What has emerged is still an ill-defined picture for either membrane, primarily for the wide range of conductances found. Interestingly, however, a few conductances (in the range of 10-80 pS) seem to be ubiquitously distributed.
MORAN O., SORGATO, MARIA CATIA
openaire   +3 more sources

Mitochondrial Membrane Permeabilization in Cell Death

Physiological Reviews, 2007
Irrespective of the morphological features of end-stage cell death (that may be apoptotic, necrotic, autophagic, or mitotic), mitochondrial membrane permeabilization (MMP) is frequently the decisive event that delimits the frontier between survival and death.
Kroemer, G.   +2 more
openaire   +3 more sources

Lipid Peroxidation in Mitochondrial Membrane

1980
Publisher Summary The principal elements of cytoplasm structure and biological membranes are the phospholipids containing unsaturated fatty acid chains. The protein constituents, amino acids, nucleotides, carbohydrates, or coenzymes do not show such lability as is typical of unsaturated fatty acids in an oxygen-rich atmosphere.
Y A, Vladimirov   +3 more
openaire   +2 more sources

Gas diffusion electrodes and membranes for CO2 reduction electrolysers

Nature Reviews Materials, 2021
Eric W Lees   +2 more
exaly  

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