Results 61 to 70 of about 280,461 (302)
Mitochondrial inner membrane in hypothyroidism [PDF]
Archives of Biochemistry and Biophysics, 1976 Abstract Inner membrane vesicles obtained from the liver mitochondria of hypothyroid and normal rats were compared. In the vesicles from hypothyroid rats the rate of ATP synthesis at 30 °C is 35–50% less than the normal rate. The Arrhenius profile for phosphorylation by such vesicles lacks the discontinuity at 21 °C that is seen with vesicles from ...
Chen, Yii-Der Ida, Hoch, Frederic L.
openaire +3 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Electron Microscope Study Of Mitochondrial 60S and Cytoplasmic 80S Ribosomes From Locusta Migratoria [PDF]
, 1974 Purified mitochondrial ribosomes (60S) have been isolated from locust flight muscle. Purification could be achieved after lysis of mitochondria in 0.055 M MgCl2.
F. Miller +5 more
core +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Transport of proteins into mitochondria [PDF]
, 1985 Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Schleyer, Manfred, Neupert, Walter
core +1 more source
The relevance of mitochondrial membrane topology to mitochondrial function
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2006 This review summarizes recent findings from electron tomography about the three-dimensional shape of mitochondrial membranes and its possible influence on a range of mitochondrial functions. The inner membrane invaginations called cristae are pleomorphic, typically connected by narrow tubular junctions of variable length to the inner boundary membrane.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
CancerGram: An Effective Classifier for Differentiating Anticancer from Antimicrobial Peptides
Pharmaceutics, 2020 Antimicrobial peptides (AMPs) constitute a diverse group of bioactive molecules that provide multicellular organisms with protection against microorganisms, and microorganisms with weaponry for competition.
Michał Burdukiewicz +6 more
doaj +1 more source
Unique and abnormal subependymal pseudocysts in a newborn with mitochondrial disease
Science Progress, 2021 Neonatal mitochondrial disease is occasionally observed in patients with intraventricular cysts in the brain. Atypical morphology is rarely seen in these cysts. Here, we report a case of neonatal lethal mitochondrial disease with IBA57 gene mutation.
Yuki Sato +10 more
doaj +1 more source
Mitochondrial outer membrane permeabilization: a focus on the role of mitochondrial membrane structural organization [PDF]
Biophysical Reviews, 2017 Apoptosis is important in regulating cell death turnover and is mediated by the intrinsic and death receptor-based extrinsic pathways which converge at the mitochondrial outer membrane (MOM) leading to mitochondrial outer membrane permeabilization (MOMP).
Siti Haji, Suhaili +4 more
openaire +2 more sources