Results 61 to 70 of about 3,790,965 (294)
Cyclic AMP Receptor Protein from Yeast Mitochondria [PDF]
, 1985 We have identified and characterized a cyclic AMP receptor protein in mitochondria of the yeast Saccharomyces cerevisiae. The binding is specific for cyclic nucleotides, particularly for cyclic AMP which is bound with high affinity (Kd of 10(-9) M) at 1 ...
Rödel, Gerhard +2 more
core +1 more source
Metalloproteases of the Inner Mitochondrial Membrane [PDF]
Biochemistry, 2017 The inner mitochondrial membrane (IM) is among the most protein-rich cellular compartments. The metastable IM subproteome where the concentration of proteins is approaching oversaturation creates a challenging protein folding environment with a high probability of protein malfunction or aggregation.
Roman M. Levytskyy +2 more
openaire +2 more sources
The mitochondrial receptor complex [PDF]
, 1993 The receptor complex in the mitochondrial outer membrane, which consists of at least seven different proteins, is responsible for the recognition and translocation of cytosolically synthesized preproteins.
Klei, Ida J. van der; id_orcid +12 more
core +2 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Mitochondrial Machineries for Protein Import and Assembly.
Annual Review of Biochemistry, 2017 Mitochondria are essential organelles with numerous functions in cellular metabolism and homeostasis. Most of the >1,000 different mitochondrial proteins are synthesized as precursors in the cytosol and are imported into mitochondria by five transport ...
Nils Wiedemann, N. Pfanner
semanticscholar +1 more source
Mitochondrial inner membrane in hypothyroidism [PDF]
Archives of Biochemistry and Biophysics, 1976 Abstract Inner membrane vesicles obtained from the liver mitochondria of hypothyroid and normal rats were compared. In the vesicles from hypothyroid rats the rate of ATP synthesis at 30 °C is 35–50% less than the normal rate. The Arrhenius profile for phosphorylation by such vesicles lacks the discontinuity at 21 °C that is seen with vesicles from ...
Chen, Yii-Der Ida, Hoch, Frederic L.
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Translocation arrest by reversible folding of a precursor protein imported into mitochondria [PDF]
, 1989 Passage of precursor proteins through translocation contact sites of mitochondria was investigated by studying the import of a fusion protein consisting of the NH2-terminal 167 amino acids of yeast cytochrome b2 precursor and the complete mouse ...
Herzog, Volker +5 more
core +1 more source
The relevance of mitochondrial membrane topology to mitochondrial function
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2006 This review summarizes recent findings from electron tomography about the three-dimensional shape of mitochondrial membranes and its possible influence on a range of mitochondrial functions. The inner membrane invaginations called cristae are pleomorphic, typically connected by narrow tubular junctions of variable length to the inner boundary membrane.
openaire +2 more sources
Emergence of the mitochondrial reticulum from fission and fusion dynamics [PDF]
, 2012 Mitochondria form a dynamic tubular reticulum within eukaryotic cells. Currently, quantitative understanding of its morphological characteristics is largely absent, despite major progress in deciphering the molecular fission and fusion machineries ...
Michael Meyer-Hermann +13 more
core +1 more source