Results 41 to 50 of about 280,461 (302)

Control of mitochondrial morphology through differential interactions of mitochondrial fusion and fission proteins. [PDF]

PLoS ONE, 2011
Mitochondria in mammals are organized into tubular networks that undergo frequent shape change. Mitochondrial fission and fusion are the main components mediating the mitochondrial shape change.
Pinwei Huang, Chad A Galloway, Yisang Yoon   +2 more
doaj   +1 more source

The Relationship between Lifespan of Marine Bivalves and Their Fatty Acids of Mitochondria Lipids

Biology, 2023
Marine bivalves belonging to the Mytilidae and Pectinidae Families were used in this research. The specific objectives of this study were: to determine the Fatty Acids (FAs) of mitochondrial gill membranes in bivalves with different lifespans, belonging ...
Aleksandra Anatolyevna Istomina, Avianna Fayazovna Zhukovskaya, Andrey Nikolaevich Mazeika, Ekaterina Andreevna Barsova, Victor Pavlovich Chelomin, Marina Alexandrovna Mazur, Olesya Alexandrovna Elovskaya, Andrey Alexandrovich Mazur, Nadezda Vladimirovna Dovzhenko, Yuliya Vladimirovna Fedorets, Alexander Alexandrovich Karpenko   +10 more
doaj   +1 more source

Naja naja oxiana Cobra Venom Cytotoxins CTI and CTII Disrupt Mitochondrial Membrane Integrity: Implications for Basic Three-Fingered Cytotoxins. [PDF]

PLoS ONE, 2015
Cobra venom cytotoxins are basic three-fingered, amphipathic, non-enzymatic proteins that constitute a major fraction of cobra venom. While cytotoxins cause mitochondrial dysfunction in different cell types, the mechanisms by which cytotoxins bind to ...
Sardar E Gasanov, Indira H Shrivastava, Firuz S Israilov, Aleksandr A Kim, Kamila A Rylova, Boris Zhang, Ruben K Dagda   +6 more
doaj   +1 more source

Mitochondrial protein import [PDF]

, 1988
Transport of nuclear-encoded precursor proteins into mitochondria includes proteolytic cleavage of aminoterminal targeting sequences in the mitochondrial matrix. We have isolated the processing activity from Neurospora crassa.
Hawlitschek, Gerhard, Schneider, Helmut, Tropschug, Maximilian, Hartl, Franz-Ulrich, Neupert, Walter, Schmidt, Bernd   +5 more
core   +1 more source

Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane

Toxins, 2020
Cardiotoxin CTII from Naja oxiana cobra venom translocates to the intermembrane space (IMS) of mitochondria to disrupt the structure and function of the inner mitochondrial membrane.
Feng Li, Indira H. Shrivastava, Paul Hanlon, Ruben K. Dagda, Edward S. Gasanoff   +4 more
doaj   +1 more source

Mitochondrial Protein Import [PDF]

, 1987
The role of nucleoside triphosphates (NTPs) in mitochondrial protein import was investigated with the precursors of N. crassa ADP/ATP carrier, F1-ATPase subunit β, F0-ATPase subunit 9, and fusion proteins between subunit 9 and mouse dihydrofolate ...
Pfanner, Nikolaus, Tropschug, Maximilian, Neupert, Walter   +2 more
core   +1 more source

Post-translational modifications and protein quality control of mitochondrial channels and transporters

Frontiers in Cell and Developmental Biology, 2023
Mitochondria play a critical role in energy metabolism and signal transduction, which is tightly regulated by proteins, metabolites, and ion fluxes. Metabolites and ion homeostasis are mainly mediated by channels and transporters present on mitochondrial
Ashlesha Kadam, Pooja Jadiya, Dhanendra Tomar   +2 more
doaj   +1 more source

The mitochondrial receptor complex [PDF]

, 1993
The receptor complex in the mitochondrial outer membrane, which consists of at least seven different proteins, is responsible for the recognition and translocation of cytosolically synthesized preproteins.
Klei, Ida J. van der; id_orcid, Pfanner, Nikolaus, Schneider, Helmut,, Kiebler, Michael,, Keil, Petra,, Kiebler, Michael, Neupert, Walter, Klei, Ida J. van der,, Klei, Ida J. van der, Pfanner, Nikolaus,, Keil, Petra, Schneider, Helmut, Neupert, Walter,   +12 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Dynamic interplay between the co-opted Fis1 mitochondrial fission protein and membrane contact site proteins in supporting tombusvirus replication.

PLoS Pathogens, 2021
Plus-stranded RNA viruses have limited coding capacity and have to co-opt numerous pro-viral host factors to support their replication. Many of the co-opted host factors support the biogenesis of the viral replication compartments and the formation of ...
Wenwu Lin, Zhike Feng, K Reddisiva Prasanth, Yuyan Liu, Peter D Nagy   +4 more
doaj   +1 more source