Results 31 to 40 of about 3,790,965 (294)

Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation

open access: yeseLife, 2017
The cytosol-facing membranes of cellular organelles contain proteins that enable signal transduction, regulation of morphology and trafficking, protein import and export, and other specialized processes.
Victoria Hung   +7 more
semanticscholar   +1 more source

Mitochondrial Fission and Fusion: Molecular Mechanisms, Biological Functions, and Related Disorders

open access: yesMembranes, 2022
Mitochondria are dynamic organelles that undergo fusion and fission. These active processes occur continuously and simultaneously and are mediated by nuclear-DNA-encoded proteins that act on mitochondrial membranes. The balance between fusion and fission
Mode Al Ojaimi   +2 more
semanticscholar   +1 more source

Hsp70 in mitochondrial biogenesis [PDF]

open access: yes, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
Stuart, Rosemary A.   +2 more
core   +1 more source

Anomalous diffusion induced by cristae geometry in the inner mitochondrial membrane [PDF]

open access: yes, 2009
Diffusion of inner membrane proteins is a prerequisite for correct functionality of mitochondria. The complicated structure of tubular, vesicular or flat cristae and their small connections to the inner boundary membrane impose constraints on the ...
Jürgen Bereiter-Hahn   +6 more
core   +2 more sources

A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission

open access: yesMolecular Biology of the Cell, 2014
Drp1 catalyzes mitochondrial division, but the mechanisms remain elusive. The mitochondrial lipid cardiolipin stimulates Drp1 activity and supports membrane constriction.
P. Macdonald   +6 more
semanticscholar   +1 more source

Mitochondrial Membrane Potential Assay [PDF]

open access: yes, 2016
Mitochondrial function, a key indicator of cell health, can be assessed by monitoring changes in mitochondrial membrane potential (MMP). Cationic fluorescent dyes are commonly used tools to assess MMP. We used a water-soluble mitochondrial membrane potential indicator (m-MPI) to detect changes in MMP in HepG2 cells.
Srilatha, Sakamuru   +2 more
openaire   +2 more sources

MOM19, an import receptor for mitochondrial precursor proteins [PDF]

open access: yes, 1989
We have identified a 19 kd protein of the mitochondrial outer membrane (MOM19). Monospecific IgG and Fab fragments directed against MOM19 inhibit import of precursor proteins destined for the various mitochondrial subcompartments, including porin ...
Söllner, Thomas   +4 more
core   +1 more source

A mitochondrial import receptor for the ADP/ATP carrier [PDF]

open access: yes, 1990
We have identified a mitochondrial outer membrane protein of 72 kd (MOM72) that exhibits the properties of an import receptor for the ADP/ATP carrier (AAC), the most abundant mitochondrial protein.
Söllner, Thomas   +4 more
core   +1 more source

Localization of HPV-18 E2 at Mitochondrial Membranes Induces ROS Release and Modulates Host Cell Metabolism

open access: yesPLoS ONE, 2013
Papillomavirus E2 proteins are predominantly retained in the nuclei of infected cells, but oncogenic (high-risk) HPV-18 and 16 E2 can shuttle between the host nucleus and cytoplasm.
Deborah Lai   +6 more
semanticscholar   +1 more source

Successive translocation into and out of the mitochondrial matrix [PDF]

open access: yes, 1987
We investigated the import and sorting pathways of cytochrome b2 and cytochrome c1, which are functionally located in the intermembrane space of mitochondria.
Ostermann, Joachim   +3 more
core   +1 more source

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