Results 11 to 20 of about 280,461 (302)
Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis
Cell Death and Disease, 2022 The recruitment of DRP1 to mitochondrial membranes prior to fission is facilitated by the wrapping of endoplasmic reticulum (ER) membranes around the mitochondria.
Rachel J. Carter +6 more
doaj +1 more source
Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5
Life Science Alliance, 2022 This study shows that lipids can act as regulators for the ubiquitination process and can control the stability and activity of a membrane-embedded E3 ubiquitin ligase. Mitochondrial homeostasis is tightly controlled by ubiquitination.
Lisa Merklinger +4 more
doaj +1 more source
Activation of AMPKα2 Is Not Required for Mitochondrial FAT/CD36 Accumulation during Exercise. [PDF]
PLoS ONE, 2015 Exercise has been shown to induce the translocation of fatty acid translocase (FAT/CD36), a fatty acid transport protein, to both plasma and mitochondrial membranes.
Cynthia Monaco +5 more
doaj +1 more source
Pathways shaping the mitochondrial inner membrane
Open Biology, 2021 Mitochondria are complex organelles with two membranes. Their architecture is determined by characteristic folds of the inner membrane, termed cristae.
Till Klecker, Benedikt Westermann
doaj +1 more source
Mitochondrial membrane potential [PDF]
Analytical Biochemistry, 2018 The mitochondrial membrane potential (ΔΨm) generated by proton pumps (Complexes I, III and IV) is an essential component in the process of energy storage during oxidative phosphorylation. Together with the proton gradient (ΔpH), ΔΨm forms the transmembrane potential of hydrogen ions which is harnessed to make ATP.
Ljubava D, Zorova +11 more
openaire +2 more sources
Unraveling the Role of Drug-Lipid Interactions in NSAIDs-Induced Cardiotoxicity
Membranes, 2020 Cardiovascular (CV) toxicity is nowadays recognized as a class effect of non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs). However, their mechanisms of cardiotoxicity are not yet well understood, since different compounds with similar action ...
Catarina Pereira-Leite +4 more
doaj +1 more source
Mitochondrial membrane models built from native lipid extracts: Interfacial and transport properties
Frontiers in Molecular Biosciences, 2022 The mitochondrion is an essential organelle enclosed by two membranes whose functionalities depend on their very specific protein and lipid compositions.
Olivia Schiaffarino +12 more
doaj +1 more source
Protein translocation across mitochondrial membranes [PDF]
, 1992 Protein translocation across biological membranes is of fundamental importance for the biogenesis of organelles and in protein secretion. We will give an overview of the recent achievements in the understanding of protein translocation across ...
Walter Neupert +3 more
core +1 more source
Transport of proteins across mitochondrial membranes [PDF]
, 1994 The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes
Neupert, Walter
core +1 more source
A morphological view on mitochondrial protein targeting [PDF]
, 1994 Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ida J. van der Klei +5 more
core +1 more source