VAMP4/STX8 Mediate the Autophagic Secretion of Mitochondria and Promote TAMs Polarization in HNSCC
ABSTRACT Under hypoxic conditions, tumour cells engage in autophagic secretion of mitochondria to sustain energy balance and modulate the tumour microenvironment. However, the exact molecular mechanisms remain unclear. This study used a combination of multivesicular bodies membrane proteomics and molecular interaction validation to demonstrate that ...
Jingcun Shi +7 more
wiley +1 more source
Mitochondrial myopathy revealed postoperative acute respiratory failure: A case report. [PDF]
Park SY +8 more
europepmc +1 more source
Serum GDF-15 Levels Accurately Differentiate Patients with Primary Mitochondrial Myopathy, Manifesting with Exercise Intolerance and Fatigue, from Patients with Chronic Fatigue Syndrome. [PDF]
Bermejo-Guerrero L +11 more
europepmc +1 more source
ABSTRACT Mitochondrial dysfunction and energy imbalance caused by chemotherapy are key contributors to skeletal muscle atrophy, which severely impacts the quality of life in cancer patients. Paclitaxel, a commonly used chemotherapeutic agent, is known to promote muscle wasting and cellular senescence, largely by impairing mitochondrial function.
Yu‐Fan Chuang +6 more
wiley +1 more source
Systemic mitochondrial involvement in mitochondrial myopathy with episodic hyper-creatine kinase-emia: insights from an autopsy case. [PDF]
Nagatomo R +14 more
europepmc +1 more source
Psychometric performance of the Primary Mitochondrial Myopathy Symptom Assessment (PMMSA) in a randomized, double-blind, placebo-controlled crossover study in subjects with mitochondrial disease. [PDF]
Gwaltney C +9 more
europepmc +1 more source
Graphical abstract describes the impact of polyphenols on signal transduction pathways involved in the development, differentiation and regeneration of muscle tissue. ABSTRACT A healthy lifestyle, characterized by moderate physical activity, appropriate caloric intake, and a diet rich in fruits and vegetables, contributes to maintaining overall health ...
Roberto Mattioli +6 more
wiley +1 more source
The profound implications of mitochondrial myopathy on activities of daily living: an observational qualitative study of standardized structured and semi-structured patient interviews. [PDF]
McCormick EM +6 more
europepmc +1 more source
ABSTRACT Background and Purpose Chronic Obstructive Pulmonary Disease (COPD) is a pulmonary condition characterized by airflow obstruction, which progresses with systemic alterations such as changes in muscle composition and metabolism, anticipating the activation of the inspiratory metaboreflex.
Natália Mota da Silva Borges +19 more
wiley +1 more source

