Results 11 to 20 of about 6,525,414 (422)

Mitochondrial proteomics: analysis of a whole mitochondrial extract with two-dimensional electrophoresis [PDF]

Methods in molecular biology (Clifton, N.J.) 432 (2008) 83-100, 2008
Mitochondria are complex organelles, and their proteomics analysis requires a combination of techniques. The emphasis in this chapter is made first on mitochondria preparation from cultured mammalian cells, then on the separation of the mitochondrial proteins with two-dimensional electrophoresis (2DE), showing some adjustment over the classical ...
A. Gorg, C. Tastet, D. Mokranjac, F. Gharahdaghi, F. Granier, H. Zischka, J. C. Sanchez, M. Chevallet, M. Eschenbruch, P. Lescuyer, S. Iwata, S. Luche, S. Luche, S. Richert, T. Rabilloud, T. Tsukihara, V. Santoni   +16 more
arxiv   +7 more sources

Sorting out mitochondrial proteins [PDF]

Trends in Cell Biology, 1993
Lill, Roland, Neupert, Walter, Stuart, Rosemary A.   +2 more
core   +6 more sources

Proteinaceous receptors for the import of mitochondrial precursor proteins [PDF]

, 1984
Mild trypsin treatment of isolated Neurospora mitochondria strongly inhibits their ability to bind and import the precursors of several mitochondrial proteins.
Neupert, Walter, Schleyer, Manfred, Zwizinski, Craig   +2 more
core   +2 more sources

Biogenesis of mitochondrial membrane proteins [PDF]

Progress in clinical and biological research, 1982
Hennig, Bernd, Hoffman, Joseph F., Neupert, Walter, Schleyer, Manfred, Schmidt, Bernd, Teintze, Martin   +5 more
core   +5 more sources

Exercise, Mitohormesis, and Mitochondrial ORF of the 12S rRNA Type-C (MOTS-c) [PDF]

Diabetes & Metabolism Journal, 2022
Low levels of mitochondrial stress are beneficial for organismal health and survival through a process known as mitohormesis. Mitohormetic responses occur during or after exercise and may mediate some salutary effects of exercise on metabolism.
Tae Kwan Yoon, Chan Hee Lee, Obin Kwon, Min-Seon Kim   +3 more
doaj   +1 more source

Assembly of mitochondrial proteins [PDF]

Horizons in biochemistry and biophysics, 1983
Hennig, Bernd, Kroon, Albertus M., Neupert, Walter   +2 more
core   +3 more sources

Molecular Basis of Rare Diseases Associated to the Maturation of Mitochondrial [4Fe-4S]-Containing Proteins

Biomolecules, 2022
The importance of mitochondria in mammalian cells is widely known. Several biochemical reactions and pathways take place within mitochondria: among them, there are those involving the biogenesis of the iron–sulfur (Fe-S) clusters.
Francesca Camponeschi, Simone Ciofi-Baffoni, Vito Calderone, Lucia Banci   +3 more
doaj   +1 more source

Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins

Nature Communications, 2021
Mislocalization of the predominantly nuclear RNA/DNA binding protein, TDP-43, occurs in motor neurons of ~95% of amyotrophic lateral sclerosis (ALS) patients, but the contribution of axonal TDP-43 to this neurodegenerative disease is unclear.
Topaz Altman, A. Ionescu, Amjad Ibraheem, Dominik Priesmann, Tal Gradus-Pery, Luba Farberov, Gayster Alexandra, N. Shelestovich, R. Dafinca, N. Shomron, F. Rage, K. Talbot, Michael E. Ward, A. Dori, M. Krüger, E. Perlson   +15 more
semanticscholar   +1 more source

Mitochondrial protein dysfunction in pathogenesis of neurological diseases

Frontiers in Molecular Neuroscience, 2022
Mitochondria are essential organelles for neuronal function and cell survival. Besides the well-known bioenergetics, additional mitochondrial roles in calcium signaling, lipid biogenesis, regulation of reactive oxygen species, and apoptosis are pivotal ...
Liang Wang, Ziyun Yang, Ziyun Yang, Ziyun Yang, Ziyun Yang, Xiumei He, Xiumei He, Xiumei He, Shiming Pu, Shiming Pu, Shiming Pu, Cheng Yang, Cheng Yang, Cheng Yang, Qiong Wu, Qiong Wu, Qiong Wu, Zuping Zhou, Zuping Zhou, Xiaobo Cen, Hongxia Zhao, Hongxia Zhao, Hongxia Zhao, Hongxia Zhao   +23 more
doaj   +1 more source

Mitochondrial protein import [PDF]

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1989
Most mitochondrial proteins are synthesized as precursor proteins on cytosolic polysomes and are subsequently imported into mitochondria. Many precursors carry amino-terminal presequences which contain information for their targeting to mitochondria. In several cases, targeting and sorting information is also contained in non-amino-terminal portions of
Hartl, Franz-Ulrich, Pfanner, Nikolaus, Nicholson, Donald W., Neupert, Walter   +3 more
openaire   +5 more sources