Results 131 to 140 of about 50,341 (179)

TSJT1 and glutamate is required for aluminum tolerance associated with mitochondrial pyruvate carrier 1 in Arabidopsis. [PDF]

Plant Signal Behav
Yuan C, He L, Chen D, Gao J, Zhang W.
europepmc   +1 more source

MSDC-0160, a novel clinical-stage mitochondrial pyruvate carrier inhibitor, suppresses osteoclast differentiation and alleviates type 2 diabetes-related bone loss. [PDF]

J Transl Med
Wang C, Hai N, Chen L, Huang Q, Gui Y, Su Y, Lian H, Liang J, Zhao J, Xu J, Liu Q.   +10 more
europepmc   +1 more source

Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice. [PDF]

J Biol Chem, 2022
Hodges WT, Jarasvaraparn C, Ferguson D, Griffett K, Gill LE, Chen Y, Ilagan MXG, Hegazy L, Elgendy B, Cho K, Patti GJ, McCommis KS, Finck BN.   +12 more
europepmc   +1 more source

A Critical Role for the Mitochondrial Pyruvate Carrier in Hepatic Stellate Cell Activation. [PDF]

Cell Mol Gastroenterol Hepatol
Habibi M, Ferguson D, Eichler SJ, Chan MM, Fu C, Pietka TA, Bredemeyer AL, LaPoint A, Shew TM, He M, Liss KHH, Lutkewitte AJ, Cho K, Schilling JD, Patti GJ, Finck BN.   +15 more
europepmc   +1 more source

Advances in the Development of Mitochondrial Pyruvate Carrier Inhibitors for Therapeutic Applications. [PDF]

Biomolecules
Politte H, Maram L, Elgendy B.
europepmc   +1 more source

Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening. [PDF]

Biomedicines, 2022
Hegazy L, Gill LE, Pyles KD, Kaiho C, Kchouk S, Finck BN, McCommis KS, Elgendy B.   +7 more
europepmc   +1 more source

Mitochondrial pyruvate carrier inhibits tumor growth by Bmi1 ubiquitination in renal cell carcinoma progression. [PDF]

Discov Oncol
Jian D, Hu N, He R, He L, Xiao H, Peng X, Peng Y, Yang Y, Dai X, Wang D, Feng Y, Dai N, Chen Q.   +12 more
europepmc   +1 more source

Withdrawal: Mitochondrial pyruvate carrier blockade results in decreased osteoclastogenesis and bone resorption via regulating mitochondrial energy production. [PDF]

J Biol Chem, 2022
Guo Q, Zhao H, Cheng H, Kang H, Dong Y, Peng R, Zhu M, Fang Z, Li F.   +8 more
europepmc   +1 more source

Disease stage-specific role of the mitochondrial pyruvate carrier suppresses differentiation in temozolomide and radiation-treated glioblastoma. [PDF]

Neuro Oncol
Martell E, Kuzmychova H, Senthil H, Chawla U, Kaul E, Grewal A, Banerji V, Anderson CM, Venugopal C, Miller D, Werbowetski-Ogilvie TE, Singh SK, Sharif T.   +12 more
europepmc   +1 more source

The Importance of Mitochondrial Pyruvate Carrier in Cancer Cell Metabolism and Tumorigenesis. [PDF]

Cancers (Basel), 2021
Ruiz-Iglesias A, Mañes S.
europepmc   +1 more source