Results 151 to 160 of about 50,341 (179)

Deoxyribonucleic ccid synthesis in isolated chloroplasts and chloroplast extracts of maize [PDF]

, 1982
Zimmermann, Wolfgang
core  

Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury. [PDF]

Mol Metab
Rauckhorst AJ, Vasquez Martinez G, Mayoral Andrade G, Wen H, Kim JY, Simoni A, Robles-Planells C, Mapuskar KA, Rastogi P, Steinbach EJ, McCormick ML, Allen BG, Pabla NS, Jackson AR, Coleman MC, Spitz DR, Taylor EB, Zepeda-Orozco D.   +17 more
europepmc   +1 more source

Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice. [PDF]

Nat Metab, 2020
McCommis KS, Kovacs A, Weinheimer CJ, Shew TM, Koves TR, Ilkayeva OR, Kamm DR, Pyles KD, King MT, Veech RL, DeBosch BJ, Muoio DM, Gross RW, Finck BN.   +13 more
europepmc   +1 more source

Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer. [PDF]

Mol Carcinog
Furusawa T, Cavero R, Liu Y, Li H, Xu X, Andresson T, Reinhold W, White O, Boufraqech M, Meyer TJ, Hartmann O, Diefenbacher ME, Pommier Y, Weyemi U.   +13 more
europepmc   +1 more source

Reduced mitochondrial pyruvate carrier expression in hearts with heart failure and reduced ejection fraction patients: ischemic vs. non-ischemic origin. [PDF]

Front Cardiovasc Med
Lopez-Vazquez P, Fernandez-Caggiano M, Barge-Caballero E, Barge-Caballero G, Couto-Mallon D, Grille-Cancela Z, Blanco-Canosa P, Paniagua-Martin MJ, Enriquez-Vazquez D, Vazquez-Rodriguez JM, Domenech N, Crespo-Leiro MG.   +11 more
europepmc   +1 more source

At last: the mitochondrial pyruvate carrier structure revealed!

Trends in Pharmacological Sciences
Brian N. Finck, Christy M. Hadfield, Kyle S. McCommis   +2 more
openaire   +1 more source

Accumulation of the phytoalexin glyceollin i in soybean nodules infected by a bradyrhizobium-japonicum-nifa mutant [PDF]

, 1991
Fischer, H., Hennecke, H., Parniske, Martin, Werner, Dietrich   +3 more
core  

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Structures and mechanism of the human mitochondrial pyruvate carrier

Nature
The mitochondrial pyruvate carrier (MPC) is a mitochondrial inner membrane protein complex that is essential for the uptake of pyruvate into the mitochondrial matrix as the primary carbon source for the tricarboxylic acid cycle1,2. Here we present six cryo-electron microscopy structures of human MPC in three states: three structures in the ...
Gaoxingyu Huang, Peilong Lu, Dan Ma
exaly   +3 more sources

Lysine acetylation regulates mitochondrial pyruvate carrier activity and cardiac pyruvate oxidation

Physiology, 2023
Background/Objective: The normal heart can acutely switch fuel sources based on delivery. While this is beneficial in physiological scenarios, this flexibility is often lost in cardiac pathologies. During fasting, blood glucose levels drop and increased free fatty acid delivery causes the heart to shut off glucose/pyruvate oxidation and increase fat ...
Thiago Menezes, Kelly Pyles, Kyle McCommis   +2 more
openaire   +1 more source