Results 1 to 10 of about 191,179 (159)

Acute Spinal Cord Injury: Correlations and Causal Relations Between Intraspinal Pressure, Spinal Cord Perfusion Pressure, Lactate-to-Pyruvate Ratio, and Limb Power. [PDF]

, 2021
BACKGROUND/OBJECTIVE: We have recently developed monitoring from the injury site in patients with acute, severe traumatic spinal cord injuries to facilitate their management in the intensive care unit.
Hogg, FRA, Kearney, S, Papadopoulos, MC, Saadoun, S, Zoumprouli, A   +4 more
core   +1 more source

The role of PASS and STITCH in the verification of unknown properties of pyruvate and lactate. Literature review and fragments of authors’ own research

Бюллетень сибирской медицины, 2023
The aim of the study was to identify the predicted spectrum of biological activity of pyruvate and lactate using modern computer modeling methods and to determine potential protein partners in intermolecular interaction.Materials and methods.
N. A. Kolotyeva, F. N. Gilmiyarova, O. A. Gusyakova, E. A. Semashkova   +3 more
doaj   +1 more source

Metabolic Engineering of Microorganisms to Produce Pyruvate and Derived Compounds

Molecules, 2023
Pyruvate is a hub of various endogenous metabolic pathways, including glycolysis, TCA cycle, amino acid, and fatty acid biosynthesis. It has also been used as a precursor for pyruvate-derived compounds such as acetoin, 2,3-butanediol (2,3-BD), butanol ...
Qian Luo, Nana Ding, Yunfeng Liu, Hailing Zhang, Yu Fang, Lianghong Yin   +5 more
doaj   +1 more source

AMPK adapts metabolism to developmental energy requirement during dendrite pruning in Drosophila

Cell Reports, 2021
Summary: To reshape neuronal connectivity in adult stages, Drosophila sensory neurons prune their dendrites during metamorphosis using a genetic degeneration program that is induced by the steroid hormone ecdysone.
Marco Marzano, Svende Herzmann, Leonardo Elsbroek, Neeraja Sanal, Katsiaryna Tarbashevich, Erez Raz, Michael P. Krahn, Sebastian Rumpf   +7 more
doaj   +1 more source

One-pot biosynthesis of N-acetylneuraminic acid from chitin via combination of chitin-degrading enzymes, N-acetylglucosamine-2-epimerase, and N-neuraminic acid aldolase

Frontiers in Microbiology, 2023
N-acetylneuraminic acid (Neu5Ac) possesses the ability to promote mental health and enhance immunity and is widely used in both medicine and food fields as a supplement.
Quanzhen Liu, Guoguang Wei, Pengfan Yang, Chengyong Wang, Kequan Chen, Pingkai Ouyang, Alei Zhang   +6 more
doaj   +1 more source

Integrated transcriptomics, proteomics and metabolomics-based analysis uncover TAM2-associated glycolysis and pyruvate metabolic remodeling in pancreatic cancer

Frontiers in Immunology, 2023
IntroductionTumor-associated macrophage 2 (TAM2) abundantly infiltrates pancreatic ductal adenocarcinoma (PAAD), and its interaction with malignant cells is involved in the regulation of tumor metabolism.
Xin Li, Yan Du, Wenkai Jiang, Shi Dong, Wancheng Li, Huan Tang, Jianfeng Yi, Jianfeng Yi, Wence Zhou, Wence Zhou, Hui Zhang, Hui Zhang   +11 more
doaj   +1 more source

Acetate and Potassium Modulate the Stationary-Phase Activation of lrgAB in Streptococcus mutans

Frontiers in Microbiology, 2020
Fluctuating environments force bacteria to constantly adapt and optimize the uptake of substrates to maintain cellular and nutritional homeostasis. Our recent findings revealed that LrgAB functions as a pyruvate uptake system in Streptococcus mutans, and
Sang-Joon Ahn, Shailja Desai, Loraine Blanco, Min Lin, Kelly C. Rice   +4 more
doaj   +1 more source

Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomes

Frontiers in Immunology, 2022
BackgroundCoronavirus-19 (COVID-19) disease is driven by an unchecked immune response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus which alters host mitochondrial-associated mechanisms.
Victòria Ceperuelo-Mallafré, Victòria Ceperuelo-Mallafré, Victòria Ceperuelo-Mallafré, Laia Reverté, Laia Reverté, Joaquim Peraire, Joaquim Peraire, Joaquim Peraire, Joaquim Peraire, Ana Madeira, Ana Madeira, Elsa Maymó-Masip, Elsa Maymó-Masip, Miguel López-Dupla, Miguel López-Dupla, Miguel López-Dupla, Miguel López-Dupla, Alicia Gutierrez-Valencia, Ezequiel Ruiz-Mateos, Maria José Buzón, Rosa Jorba, Rosa Jorba, Rosa Jorba, Joan Vendrell, Joan Vendrell, Joan Vendrell, Joan Vendrell, Teresa Auguet, Teresa Auguet, Teresa Auguet, Montserrat Olona, Montserrat Olona, Montserrat Olona, Montserrat Olona, Francesc Vidal, Francesc Vidal, Francesc Vidal, Francesc Vidal, Anna Rull, Anna Rull, Anna Rull, Anna Rull, Sonia Fernández-Veledo, Sonia Fernández-Veledo   +43 more
doaj   +1 more source

Nutritional Status of Tuberculosis Patients in Against Serum Glutamate Pyruvate Transaminase Levels

Magna Medika, 2021
Background: Treatment of Tuberculosis patients are given in the form of a drugs combination. Some drugs which are Pyrazinamide, Isoniazid and Rifampicin can provide hepatotoxic side effects.
Iqbal Donarika Widagdo, Setyoko Setyoko, M. Riza Setiawan   +2 more
doaj   +1 more source

In vivo metabolic imaging of Traumatic Brain Injury. [PDF]

, 2017
Complex alterations in cerebral energetic metabolism arise after traumatic brain injury (TBI). To date, methods allowing for metabolic evaluation are highly invasive, limiting our understanding of metabolic impairments associated with TBI pathogenesis ...
Chaumeil, Myriam M, Chou, Austin, Feng, Xi, Guglielmetti, Caroline, Krukowski, Karen, Najac, Chloe, Riparip, Lara-Kirstie, Rosi, Susanna   +7 more
core   +2 more sources