Results 21 to 30 of about 296,841 (265)

Adição de piruvato de sódio e trolox ao diluidor utilizado para congelação de sêmen de garanhões férteis e subférteis Effect of pyruvate and trolox added to the extender used for freezing fertile and subfertile stallion semen

Ciência Rural, 2008
O objetivo deste trabalho foi avaliar o efeito do piruvato e trolox (forma solúvel da vitamina E) sobre a qualidade espermática pós-descongelamento. Assim, com o intuito de proteger as células espermáticas dos efeitos deletérios da criopreservação,foram ...
Karen Mascaro Gonçalves da Silva, Sandra Cristina Gamboa, Ana Sofia Rodrigues, João Ramalho Santos, Maria Madalena Pessoa Guerra   +4 more
doaj   +1 more source

CO2-Induced Transcriptional Reorganization: Molecular Basis of Capnophillic Lactic Fermentation in Thermotoga neapolitana

Frontiers in Microbiology, 2020
Capnophilic lactic fermentation (CLF) is a novel anaplerotic pathway able to convert sugars to lactic acid (LA) and hydrogen using CO2 as carbon enhancer in the hyperthermophilic bacterium Thermotoga neapolitana.
Giuliana d’Ippolito, Simone Landi, Nunzia Esercizio, Mariamichella Lanzilli, Marco Vastano, Laura Dipasquale, Nirakar Pradhan, Angelo Fontana   +7 more
doaj   +1 more source

The 150 most important questions in cancer research and clinical oncology series: questions 102–104

Visualized Cancer Medicine
To accelerate our endeavors to overcome cancer, Visualized Cancer Medicine continues the previously launched program of publishing the 150 most important questions in cancer research and clinical oncology.
Lu Zhimin
doaj   +1 more source

Neuronal Death in Cultured Murine Cortical Cells Is Induced by Inhibition of GAPDH and Triosephosphate Isomerase

Neurobiology of Disease, 1998
Polyglutamine-containing proteins expressed in the CAG repeat diseases Huntington's disease and dentatorubralpallidoluyisian atrophy have recently been suggested to inhibit the key glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH).
Christian T. Sheline, Dennis W. Choi
doaj   +1 more source

Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma

eLife
A glaucoma polygenic risk score (PRS) can effectively identify disease risk, but some individuals with high PRS do not develop glaucoma. Factors contributing to this resilience remain unclear.
Keva Li, Nicholas Tolman, Ayellet V Segrè, Kelsey V Stuart, Oana A Zeleznik, Neeru A Vallabh, Kuang Hu, Nazlee Zebardast, Akiko Hanyuda, Yoshihiko Raita, Christa Montgomery, Chi Zhang, Pirro G Hysi, Ron Do, Anthony P Khawaja, Janey L Wiggs, Jae H Kang, Simon WM John, Louis R Pasquale, UK Biobank Eye and Vision Consortium   +19 more
doaj   +1 more source

Lactate/pyruvate monitoring during carotid endarterectomy under general anaesthesia versus cervical plexus block: A randomised controlled study

Indian Journal of Anaesthesia, 2017
Background and Aims: Carotid endarterectomy (CEA) reduces the risk of stroke in patients with significant carotid stenosis and may be performed under general anaesthesia (GA) or regional anaesthesia (RA). This study aimed to compare RA and GA with regard
Gomaa Z Hussien, Ahmed M Elbadawy, Hossam A Elshamaa   +2 more
doaj   +1 more source

Microdialysis monitoring of CSF parameters in severe traumatic brain injury patients: A novel approach

Frontiers in Neurology, 2014
Background: Neuro-intensive care following traumatic brain injury is focused on preventing secondary insults that may lead to irreversible brain damage. Microdialysis (MD) is used to detect deranged cerebral metabolism.
Eric Peter Thelin, David W Nelson, Bo-Michael eBellander   +2 more
doaj   +1 more source

Physicochemical Properties, Biological Activity, Health Benefits, and General Limitations of Aged Black Garlic: A Review

Molecules, 2017
Garlic (Allium sativum) has been used as a medicinal food since ancient times. However, some people are reluctant to ingest raw garlic due to its unpleasant odor and taste.
Ji Hyeon Ryu, Dawon Kang
doaj   +1 more source

Conformational features of lactate dehydrogenase: temperature effect in presence of small molecules, mathematical model

Бюллетень сибирской медицины, 2020
The aim of this work was to study the conformational changes of lactate dehydrogenase under the influence of different concentrations of intermediates (pyruvate, oxaloacetate) in the temperature gradient with the  subsequent building of a mathematical ...
F. N. Gilmiyarova, V. I. Kuzmicheva, N. A. Kolotyeva, M. V. Komarova, E. A. Ryskina, O. A. Gusyakova, D. S. Vinogradova, V. V. Salmin   +7 more
doaj   +1 more source

The role of PASS and STITCH in the verification of unknown properties of pyruvate and lactate. Literature review and fragments of authors’ own research

Бюллетень сибирской медицины, 2023
The aim of the study was to identify the predicted spectrum of biological activity of pyruvate and lactate using modern computer modeling methods and to determine potential protein partners in intermolecular interaction.Materials and methods.
N. A. Kolotyeva, F. N. Gilmiyarova, O. A. Gusyakova, E. A. Semashkova   +3 more
doaj   +1 more source